Background: To investigate the level of ganciclovir in the aqueous humour (AH) following topical application of 2.0% ganciclovir eye drop in eyes with cytomegalovirus (CMV) anterior segment infection.
Methods: This is a prospective, non-randomised, interventional clinical study.
Open Forum Infect Dis
December 2021
endophthalmitis is a serious complication of candidemia. Diagnosis requires identification of ocular lesions on dilated fundoscopy, aided by isolation of the organism from blood and/or vitreous humor. However, the initial ophthalmological examination may be negative in some cases.
View Article and Find Full Text PDFOcul Immunol Inflamm
November 2021
: To describe the demographics and clinical characteristics of pediatric uveitis and scleritis at a tertiary eye care center.: Clinical records of children with either uveitis or scleritis that presented between January 1989 and January 2016 were reviewed retrospectively.: Seventy-three patients were identified.
View Article and Find Full Text PDFPurpose: To investigate the intra-cameral level of ganciclovir following topical application of ganciclovir gel, 0.15% for cytomegalovirus (CMV) anterior segment infection.
Design: Non-randomized, prospective, interventional clinical study.
Ocul Immunol Inflamm
July 2018
Purpose: To describe the pattern of uveitis among Chinese, Malays, and Indians at a tertiary referral institution in Singapore.
Methods: Charts between January 1997 and December 2010 were retrospectively reviewed. Charts between January 2014 and December 2014 were prospectively reviewed.
Objectives: To evaluate the suitablity of commercially available moisture retention eyewear for treating evaporative dry eye.
Methods: Eleven patients with evaporative dry eyes were prescibed moisture retention eyewear for 3 months in addition to regular lubricant eye drops. Frequency and severity of dry eye symptoms, corneal fluorescein staining and tear break up time (TBUT) were evaluated at baseline and 3-month post-treatment.
Purpose: To investigate the efficacy of a lubricant eye drop containing gelling agent in adult Chinese dry eye patients.
Methods: This is a prospective, randomized, double-masked, double-arm, parallel, interventional single-site clinical study. Thirty Chinese dry eye patients were randomized into two arms, 15 patients each, receiving lubricant eye drops either containing hydroxypropyl-guar (HP-guar) gelling agent (Systane Ultra) or no gelling agent (Refresh Tears), 1 drop, four times a day for 6 weeks.
Aim: To study the differences in aqueous cytokines in Posner-Schlossman Syndrome (PSS) patients with and without human cytomegalovirus (CMV) DNA in the aqueous humor.
Methods: This is a prospective study. Fifty-three uveitis patients with clinical signs of PSS were enrolled and aqueous humor samples were collected.
Objectives: To estimate the cost and patterns of expenditure of dry eye treatment.
Methodology: We retrieved data on the type and cost of dry eye treatment in Singapore National Eye Centre from pharmacy and clinic inventory databases over a 2 year period (2008-2009) retrospectively. According to the type of treatment, data were sorted into 7 groups; meibomien gland disease (MGD) treatment, preservative free lubricant eye drops, preserved lubricant eye drops, lubricant ointments and gels, cyclosporine eye drops, oral supplements and non-pharmacological treatments/procedures.