Publications by authors named "Samantha R Logan"
Article Synopsis
- Members of the family and genus mentioned are important emerging pathogens affecting both ecology and the economy.
- In 2017, a die-off of wood and boreal chorus frogs in Canada's Wood Buffalo National Park was linked to a newly identified ranavirus (RSR) with a significant genetic similarity to the well-known frog virus 3 (FV3).
- The study emphasizes the relevance of detailed viral genomic analysis, especially for understanding the distribution and genetic traits that influence how these viruses may infect different host species and cause disease.
Cytokinins (CKs) are a group of N-substituted signaling molecules whose biosynthesis and metabolism have been documented in all kingdoms of life, including vertebrates. While their biological relevance in vertebrate systems continues to be elucidated, they have broadly been documented with therapeutic effects in exogenous applications. In this study, we evaluated the virostatic potential of four types of CKs including, -isopentenyladenine (iP), -isopentenyladenosine (iPR), -isopentenyladenosine-5'monophosphate (iPMP), and 2-methylthiol--isopentenyladenosine (2MeSiPR) against the ranavirus type species, frog virus 3 (FV3).
View Article and Find Full Text PDFViruses are obligate intracellular parasites that alter host metabolic machinery to obtain energy and macromolecules that are pivotal for replication. , including the type species of the genus frog virus 3 (FV3), represent an ecologically important group of viruses that infect fish, amphibians, and reptiles. It was established that fatty acid synthesis, glucose, and glutamine metabolism exert roles during iridovirus infections; however, no information exists regarding the role of purine metabolism.
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