Publications by authors named "Samantha R Debes"
Attention improves perception by enhancing the neural encoding of sensory information. A long-standing hypothesis is that cortical feedback projections carry top-down signals to influence sensory coding. However, this hypothesis has never been tested to establish causal links.
View Article and Find Full Text PDFBrain state limits propagation of neural signals in laminar cortical circuits.
Proc Natl Acad Sci U S A
July 2022
Our perception of the environment relies on the efficient propagation of neural signals across cortical networks. During the time course of a day, neural responses fluctuate dramatically as the state of the brain changes to possibly influence how electrical signals propagate across neural circuits. Despite the importance of this issue, how patterns of spiking activity propagate within neuronal circuits in different brain states remains unknown.
View Article and Find Full Text PDFArticle Synopsis
- Optogenetics has transformed neuroscience research in small animals, but its effectiveness in non-human primates (NHPs) has shown mixed results.
- * A centralized database has been created to help researchers track both successful and unsuccessful optogenetic experiments in primates, with contributions from 45 laboratories worldwide.
- * The database, available on the Open Science Framework, aims to enhance research by sharing over 1,000 injection experiments and offers insights to improve optogenetic methods in NHPs.*