Risks and benefits of pre-delivery taper in pregnant women taking antidepressants.

Background: Serotonin reuptake inhibitors are commonly used for treatment of mental health problems in pregnancy but may cause neonatal adaptation syndrome. It is unknown whether reduction or discontinuation of medication prior to delivery may mitigate this effect.

Methods: We present a case series of 38 women who either tapered their medication prior to delivery or maintained or increased their dose.