Publications by authors named "Samantha Lowry"
Front Immunol
October 2024
Article Synopsis
- Psoriasis is driven by immune cell interactions, with a focus on S1PR2, which hasn’t been thoroughly explored before, despite other S1PR antagonists showing promise in treatment.
- Using techniques like spatial transcriptomics and flow cytometry, researchers studied how S1PR2 impacts immune responses in a mouse model of psoriasis.
- The findings indicate that S1PR2 in keratinocytes helps regulate inflammation by inhibiting Th17 cell recruitment, suggesting that activating S1PR2 might offer a new treatment strategy for psoriasis.
