Background: This study investigated the prevalence, risk factors and severity of corneal tomographic features of keratoconus in Down syndrome (DS). Additionally, previous studies indicate anomalous corneal features in DS, without keratoconus, this study characterised corneal features in DS without keratoconus.
Methods: This prospective observational study included participants with DS ≥10 years old.
Background: We wish to determine the prevalence and risk factors of incomplete peripheral avascular retina (IPAR) in children screened for retinopathy of prematurity (ROP) and its association with oxygen saturation (SpO) targets.
Methods: A retrospective review of retinal images of premature infants born and screened for ROP in Auckland Region, New Zealand, between January 2013 and December 2017 was conducted. Images were reviewed to determine if avascular retina was present at their final ROP screening.
Penguins (Spheniscidae) are a diverse clade of flightless, marine birds. Their eyes, likely a primary driver of behaviour, have been noted to have anatomic adaptations to their amphibious lifestyle. In particular, they have a relatively flat cornea, which would make the transition from a subaerial to a submarine environment require less accommodative effort.
View Article and Find Full Text PDFClinical Relevance: Children with a history of regressed retinopathy of prematurity (ROP) are at increased risk of peripheral avascular retina. Wide-field digital retinal imaging and telemedicine is an effective tool for ROP screening. Ophthalmologists and Optometrists should have a high level of clinical suspicion for peripheral retinal changes in children screened for ROP.
View Article and Find Full Text PDFThe trisomy of chromosome 21, the smallest autosome, is associated with significant systemic manifestations in addition to intellectual disability. The triplication of this chromosome, known as Down syndrome (DS) is also associated with several manifestations in the eye, and ocular adnexae. People with DS have a variety of ophthalmic conditions, some of which require intervention.
View Article and Find Full Text PDFClin Exp Ophthalmol
December 2020
Importance: Keratoconus disproportionately affects people with Down syndrome (DS). This is the first study of its kind in Australasia.
Background: To investigate the prevalence of keratoconus in DS.
J Pediatr Ophthalmol Strabismus
July 2019
Purpose: To investigate persistent avascular retina in infants with type 2 retinopathy of permaturity (ROP) that persisted after 45 weeks' post-menstrual age when regular ROP screening ceased.
Methods: A prospective observational study where fundus fluorescein angiography (FFA) was completed on consecutive infants who had a history of type 2 ROP and avascular retina during ROP screening that persisted after 45 weeks' post-menstrual age.
Results: FFA was completed on 72 eyes of 36 infants (53% male), with a mean gestational age of 26.
Importance: Retinopathy of prematurity (ROP) is a potentially blinding condition affecting the retinae of premature infants. Effective screening is necessary for timely treatment.
Background: The Auckland Regional Telemedicine ROP (ART-ROP) network, utilizes wide-field digital imaging for ROP screening.
Objective: Early detection of ocular abnormalities in newborn infants is essential for timely diagnosis and treatment. This study aimed to assess wide-field digital imaging for universal newborn eye screening (UNES) to determine the prevalence of ocular abnormalities, including retinal haemorrhages, in newborn infants in New Zealand.
Design: Prospective ocular screening study of infants.
Background: Common paediatric perimetry techniques require central fixation and subjective responses, which may be challenging for young or cognitively impaired children. The Saccadic Vector Optokinetic Perimeter (SVOP) was designed to overcome these challenges by using infra-red eye tracking to assess the visual field. This study assessed the clinical feasibility of SVOP in children without visual impairment, comparing it to current paediatric techniques, and in children with visual impairment.
View Article and Find Full Text PDFPurpose: Children may be tested with a variety of visual acuity (VA) charts during their ophthalmic care and differences between charts can complicate the interpretation of VA measurements. This study compared VA measurements across four pediatric charts with Sloan letters and identified chart design features that contributed to inter-chart differences in VA.
Methods: VA was determined for right eyes of 25 adults and 17 children (4-9 years of age) using Crowded Kay Pictures, Crowded linear Lea Symbols, Crowded Keeler logMAR, Crowded HOTV and Early Treatment of Diabetic Retinopathy Study (ETDRS) charts in focused and defocused (+1.