Publications by authors named "Samantha Jayasinghe"

Problem Description: Musculoskeletal (MSK) anatomy and pathology from a radiology perspective can be difficult to conceptualize and understand due to the challenge of visualizing 3D structures in stacks of 2D imaging. Consequently, trainees may benefit from inexpensive methods that can help trainees better visualize MSK anatomy and pathology. The purpose of this study is to provide proof of concept for inexpensive methodology to help learners such as radiology residents quickly and inexpensively understand musculoskeletal anatomy and pathology.

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 Die punch (DP) fragments are among the most common fracture fragments to lose reduction after volar locked plating of articular distal radius fractures (DRFs). We aimed to report the number of patients in our institution who had a computed tomography (CT)-confirmed DP fragment and who had open reduction and internal fixation (ORIF) through a dorsal approach; to report the length of the radioulnar portion of the DP fragment relative to the total distal radioulnar joint (DRUJ) length; and to identify if an association exists between this length and the choice for a volar versus a dorsal operative approach to the DP fragment.  We performed measurements on the preoperative CT scans of 94 skeletally mature patients with a DP fragment.

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Background: Thoracic duct embolization (TDE) has become the standard treatment for atraumatic and traumatic chylothoraces. Numerous approaches to embolization including intranodal lymphangiography, transabdominal, and retrograde catheterization of the thoracic duct have become the preferred methods for the treatment of chyle leaks. The purpose of this study was to determine training, treatment techniques, outcomes, and practice patterns of practitioners performing TDE.

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Micro-RNAs (miRNAs) are a class of small non-coding RNAs, recently emerged as a post-transcriptional regulator having a key role in various cardiac pathologies. Among them, cardiac fibrosis that occurs as a result from an imbalance of extracellular matrix proteins turnover and is a highly debilitating process that eventually lead to organ dysfunction. An emerging theme on is that miRNAs participate in feedback loop with transcription factors that regulate their transcription.

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