Publications by authors named "Samantha J Boog"
Background: The emergence of resistance to the artemisinins which are the current mainstays for antimalarial chemotheraphy has created an environment where the development of new drugs acting in a mechanistally discrete manner is a priority.
Objective: The goal of this work was to synthesize ane evaluate bis-thiosemicarbazones as potential antimalarial agents.
Methods: Fifteen compounds were generated using two condensation protocols and evaluated in vitro against the NF54 (CQ sensitive) strain of Plasmodium falciparum.