Publications by authors named "Samantha Gogel"
Article Synopsis
- The study aimed to evaluate a new MRI technique to assess lung aeration in children, especially focusing on those with thoracic insufficiency syndrome (TIS).
- Researchers used standardized signal intensity (sSI) measurements from MRI scans of both healthy children and TIS patients to determine lung function pre- and post-surgery.
- Results indicated that the MRI method can detect lung aeration changes, showing a general decrease in lung sSI after surgery, although the changes were not statistically significant.
Background: The diaphragm is a critical structure in respiratory function, yet in-vivo quantitative description of its motion available in the literature is limited.
Research Question: How to quantitatively describe regional hemi-diaphragmatic motion and curvature via free-breathing dynamic magnetic resonance imaging (dMRI)?
Study Design And Methods: In this prospective cohort study we gathered dMRI images of 177 normal children and segmented hemi-diaphragm domes in end-inspiration and end-expiration phases of the constructed 4D image. We selected 25 points uniformly located on each 3D hemi-diaphragm surface.
Article Synopsis
- Thoracic insufficiency syndrome (TIS) restricts respiratory function due to spinal and thoracic deformities, making corrective orthopedic surgery a potential solution to improve lung space and diaphragm movement.
- A study involving 149 TIS pediatric patients and 190 healthy controls used free-breathing dynamic MRI to analyze diaphragm motion and changes before and after surgery.
- Results showed significant increases in diaphragm mobility, particularly in the posterior regions, with the surgery having a more pronounced effect on diaphragm function than spinal curve reductions.
Article Synopsis
- A new database called VGC has been created to measure respiratory parameters in healthy children, aimed at filling the gap in existing normative data.
- The study analyzed 3D respiratory measurements across different age and gender groups, finding significant differences in lung function, particularly among adolescents.
- Results suggest that the VGC database can help assess respiratory abnormalities in patients with conditions like TIS, aiding in treatment planning and evaluation of surgical outcomes.
Purpose: There is a concern in pediatric surgery practice that rib-based fixation may limit chest wall motion in early onset scoliosis (EOS). The purpose of this study is to address the above concern by assessing the contribution of chest wall excursion to respiration before and after surgery.
Methods: Quantitative dynamic magnetic resonance imaging (QdMRI) is performed on EOS patients (before and after surgery) and normal children in this retrospective study.