CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease.

Diseases of the renal filtration unit-the glomerulus-are the most common cause of chronic kidney disease. Podocytes are the pivotal cell type for the function of this filter and focal-segmental glomerulosclerosis (FSGS) is a classic example of a podocytopathy leading to proteinuria and glomerular scarring. Currently, no targeted treatment of FSGS is available.

The Relationship Between the Effectiveness of Blood Pressure Control and Telomerase Reverse Transcriptase Concentration, Adipose Tissue Hormone Concentration and Endothelium Function in Hypertensives.

Background: This study aimed to evaluate the relationship between the effectiveness of blood pressure (BP) control and telomerase reverse transcriptase concentration (TERT), the concentration of adipose tissue hormones and endothelium function in hypertensive patients.

Methods: The study group included 94 people with arterial hypertension. Two subgroups were distinguished according to effective BP control during 24-hour ambulatory blood pressure monitoring (ABPM): Group A - effective BP control (n=49) and Group B - ineffective BP control (n=45).

Blood Circulating miRNAs as Cancer Biomarkers for Diagnosis and Surgical Treatment Response.

miRNAs can function as potential oncogenes or tumor suppressors. Altered expression of these molecules was correlated with the occurrence of many cancer diseases and therefore they are considered a molecular tool for non-invasive cancer diagnosis and prognosis. We searched for analyses concerning expression of blood circulating miRNA in cancer patients.