Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models.

Objectives: Bromelain, a mixture of proteolytic enzymes from pineapple () is known as a potential debriding agent in burn treatment. In this research, the debridement efficiency of chitosan hydrogel loaded by sodium alginate-chitosan nanoparticles (NPs) containing bromelain (Br 10%-AG-CS NPs) was evaluated in animal models.

Materials And Methods: The NPs were prepared using the ionic gelation technique and their properties were identified.

Bromelain-loaded chitosan nanofibers prepared by electrospinning method for burn wound healing in animal models.

Bromelain is a mixture of proteolytic enzymes present in all tissues of pineapple (Ananas comosus). It is known as an efficient debriding agent in burn treatment. In this study, the efficiency of bromelain-loaded chitosan nanofibers for burn wounds repair was investigated in animal model.

Detection of simulated periodontal defects using cone-beam CT and digital intraoral radiography.

Objectives:: This study sought to assess the diagnostic value of CBCT and digital intraoral radiography for the detection of periodontal defects in the sheep mandible.

Methods:: In this in vitro study, 80 periodontal defects including Grades I, II and III furcation involvements, one-, two-, three-wall and trough-like infrabony defects, fenestration and dehiscence were artificially created in the sheep mandible by burr. Intraoral digital radiographs using photostimulable phosphor plates and CBCT scans were obtained.