Bardet-Biedl syndrome (BBS) is a rare genetically heterogeneous ciliopathy which accompanies retinitis pigmentosa (RP). However, the BBS5 mutation remains unclear in Iranians with BBS. The purpose of study is to evaluate genetic analyses of a BBS Iranian family using targetted exome sequencing (TES).
View Article and Find Full Text PDFPurpose: This study compares the corneal biomechanical properties, as measured with Corvis ST, in three groups of cases with delayed-onset mustard gas keratopathy (DMGK), chronic corneal scarring (CCS), and those with normal corneas.
Methods: Forty-five eyes were enrolled in the DMGK, CCS, and normal groups (15 eyes each). All patients were examined with the slitlamp and Corvis ST.
Leber congenital amaurosis (LCA) is a heterogeneous, early-onset inherited retinal dystrophy, which is associated with severe visual impairment. We aimed to determine the disease-causing variants in Iranian LCA and evaluate the clinical implications. Clinically, a possible LCA disease was found through diagnostic imaging, such as fundus photography, autofluorescence and optical coherence tomography.
View Article and Find Full Text PDFBackground: This study aimed to determine the prevalence of hearing impairment (HI) by age and gender in a population aged 5 yr and older residing in Tehran, Iran.
Methods: In this cross-sectional study, 140 clusters each including 10 households from Tehran, Iran were sampled between 2012 and 2013 using cluster random sampling. Trained audiologists examined the participants during face-to-face interviews.
Purpose: To determine the rate of excimer laser refractive surgery in Iran and its trend during 2010-2014, and the number of surgeries per ophthalmologist.
Methods: Twelve provinces were considered for the study; 4 major referral provinces of Tehran, Fars, Isfahan, and Khorasan, and 8 others which were selected randomly. Then a number of excimer laser centers were chosen from each province.
Purpose: To determine intraoperative complications of cataract surgery over the period 2006 to 2010.
Methods: In this cross-sectional study, 106 of 272 cataract surgical centers in Iran were selected through multistage random cluster sampling from all provinces. In each province, the selected number of centers was proportionate to the number of cataract surgeries, and in each center, the selected number of charts was proportionate to the center's number of cataract surgeries, from which we retrieved intraoperative complications.
Purpose: To determine the distribution of the anterior chamber angle (ACA) and anterior chamber volume (ACV) in an Iranian population of 40- to 64-year-old people using the Pentacam.
Methods: In this cross-sectional study, multistage sampling was used to select 300 clusters, including 6,311 individuals from the city of Shahroud. All selected participants underwent examinations in one place.
Purpose: The purpose of this study was to determine the prevalence of a history of ocular trauma and its association to age, sex, and biometric components.
Materials And Methods: Residents of Shahroud, Iran aged 40-64 years, were sampled through a cross-sectional study using multistage cluster sampling. Three hundred clusters were randomly selected, and 20 individuals were systematically selected from each cluster.
Background: Central venous catheterization (CVC) is an important procedure in emergency departments (EDs). Despite existence of ultrasonography (US) devices in every ED, CVC is done using anatomical landmarks in many EDs in Iran.
Objectives: This study aimed to compare the traditional landmark method vs.
Purpose: To determine the prevalence of tropia and phoria in Iran and their association with some related factors.
Methods: In a cross-sectional population-based study, multistage randomized cluster sampling was used to select participants from among grade 1 students in the primary schools of 7 cities of Iran. After obtaining their parents' approval, the students underwent the measurement of uncorrected and corrected visual acuity, cycloplegic refraction, and cover test.
Purpose: To determine the prevalence of amblyopia in schoolchildren aged 7 years in Iran, its relation with refractive errors, and its determinants.
Methods: In this cross-sectional study, cluster sampling was done from elementary school students in 7 cities in Iran. In all schools, an optometrist conducted all tests, including measurement of uncorrected and corrected visual acuity, cycloplegic refraction, and cover test.
Unlabelled: Background Respiratory diseases/syndromes are the most common causes of referring to physicians among pilgrims in Hajj. They lead to high morbidity, impose high costs on the health system and are among the major obstacles for pilgrims to perform Hajj duties. The main aim of our study was to determine types, frequencies, etiologies, and epidemiologic factors of respiratory diseases among Iranian Hajj pilgrims and to suggest some preventive and treatment strategies.
View Article and Find Full Text PDFBackground: The Iraq-Iran war was one of the longest conflicts in the twentieth century. The aim of our research was to review the incidence of mortality and injuries of the war.
Methods: A search strategy was designed and run in Medline, EMBASE, Scopus, and Iranian databases including Scientific Information Database (SID), IranMedex, and Magiran.
Objective: The aim of this study was to compare the Persian version of the wechsler intelligence scale for children - fourth edition (WISC-IV) and cognitive assessment system (CAS) tests, to determine the correlation between their scales and to evaluate the probable concurrent validity of these tests in patients with learning disorders.
Methods: One-hundered-sixty-two children with learning disorder who were presented at Atieh Comprehensive Psychiatry Center were selected in a consecutive non-randomized order. All of the patients were assessed based on WISC-IV and CAS scores questionnaires.