Management of early group A streptococcus fasciitis by imaging-guided percutaneous drainage.

Group A streptococcus (GAS) is associated with a spectrum of soft-tissue infections that include toxic shock syndrome, myositis, and necrotizing fasciitis (1, 2, 3). The mainstay of therapy for invasive GAS soft-tissue infections is surgical exploration and debridement, as penicillin treatment alone is associated with a high morbidity and mortality (4). We report a case that suggests that imaging-guided percutaneous drainage may have a role in the treatment of some cases of GAS fasciitis, and may preclude the need for surgical intervention.

Detection and classification of neurotoxins using a novel short-term plasticity quantification method.

A tissue-based biosensor is described for screening chemical compounds that rapidly affect the nervous system. The proposed sensor is an extension of a previous work on cultured hippocampal slices [Biosens. Bioelectron.