Publications by authors named "Samaisuk Sophasan"
Anticancer Res
September 2007
Article Synopsis
- VR3848 is a new cycloheptapeptide from a Euphorbiaceae plant that shows potential in stopping the growth of various tumor cells at very low doses.
- In studies using MCF-7 cancer cells, significant changes in genes related to apoptosis and cell cycle regulation were observed, indicating that VR3848 triggers multiple pathways for cell death.
- The three main apoptotic pathways identified include death receptor-mediated apoptosis, ER-stress-induced apoptosis, and mitochondrial membrane leakage, all contributing to the inhibition of cancer cell growth.
