Biological effect of the nanocrystalline calcium sulfate bone graft in the periodontal regeneration.

Background: The ultimate goal of tissue engineering is to reproduce functional alveolar∖Periodontal complex. This study aimed to asses micro- and nano-formulated crystalline calcium sulfate as possible treatment of intrabony defect utilizing an autologous Platelet rich fibrin scaffold.

Subjects: and Methods: An experimental prospective split mouth design using eight healthy mongrel dog's was conducted.