Publications by authors named "Samah Himayda"
Background: The primary perioperative concern during laparoscopic myomectomy is the risk of significant intraoperative blood loss, which can lead to hypovolemia, necessitate blood transfusion, and result in postoperative anemia. To address this issue, we conducted a systematic review and meta-analysis to assess the impact of temporarily clamping the uterine and utero-ovarian arteries on operative blood loss during laparoscopic myomectomy.
Methods: We conducted a comprehensive search across various databases to identify eligible clinical trials from inception to May 2024, focusing on randomized controlled trials (RCTs).
Article Synopsis
- This study conducted a meta-analysis of randomized controlled trials comparing preoperative misoprostol to control treatments in women undergoing abdominal myomectomies, covering data from six databases until April 2024.
- It analyzed 16 trials involving 975 women and found many studies had a low quality or biases, but the results indicated that misoprostol significantly reduced intraoperative blood loss, hemoglobin drop, and the need for blood transfusions compared to control.
- Additionally, misoprostol led to shorter operative times and hospital stays, although there was no significant difference in postoperative fever rates between the two groups.
Objective: To compare letrozole in combination with gonadotropins versus letrozole monotherapy in ovulation induction and clinical pregnancy among infertile women with polycystic ovarian syndrome (PCOS).
Methods: Several databases were searched for available clinical trials from inception until March 2023. We selected randomized controlled trials (RCTs) that compared sequential letrozole/gonadotropin versus letrozole alone among infertile women who met the Rotterdam criteria for PCOS.
Objectives: To assess the prognostic value of human epididymis protein 4 (HE4) kinetics during and after neoadjuvant chemotherapy (NACT) cycles compared with cancer antigen 125 (CA-125), in predicting the surgical outcomes of interval debulking surgery (IDS) in patients with advanced-stage, high-grade serous ovarian cancer.
Methods: This retrospective cohort study was conducted at Severance Hospital in Seoul, South Korea and involved 123 women with high-grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who were diagnosed between April 2015 and July 2020. Three outcomes were considered: the chemotherapy response score (CRS) by omentum, residual disease after IDS, and recurrence.
Aim: To perform a systematic review and meta-analysis of all randomized placebo-controlled trials (RCTs) that inspected the analgesic benefits of intraperitoneal lidocaine instillation among patients undergoing abdominal hysterectomy.
Methods: Five electronic databases were inspected from till August 5, 2021. The eligible RCTs were evaluated for risk of bias.