Risk factors of primary and secondary restless legs syndrome among a middle-aged population in Saudi Arabia: A community-based study.

Introduction: Restless legs syndrome (RLS) is etiologically divided into primary and secondary syndromes. However, a comparative description of both types is lacking in the literature. We compared primary and secondary RLS with respect to demographic determinants, associated risk factors, and comorbidities.

The Association Between Vitamin D Level and Restless Legs Syndrome: A Population-Based Case-Control Study.

Study Objectives: The pathophysiology of restless legs syndrome (RLS) may be related to abnormalities in central dopamine pathways. Vitamin D may play a role in the pathophysiology of RLS by modulating the dopaminergic system. The aim of our study is to examine the possible link between RLS and vitamin D deficiency.