Underestimated and unreported prolonged QTc by automated ECG analysis in patients on methadone: can we rely on computer reading?

Background: Recognition of prolonged corrected QT (QTc) interval is of particular importance, especially when using medications known to prolong QTc interval. Methadone can prolong the QTc interval and has the potential to induce torsades de pointes.

Objective: The objective of this study is to investigate the accuracy of computerized ECG analysis in correctly identifying and reporting QTc interval in patients on methadone.