Publications by authors named "Sam Piechota"
Chem Res Toxicol
February 2020
Article Synopsis
- A molecular initiating event (MIE) is the first step in a sequence that can lead to harmful effects from chemical exposure, and in silico models help predict these MIEs for better chemical risk assessment.
- Researchers developed structural alert-based models and Random Forest models to analyze 90 key human biological targets, achieving high accuracy rates (92% and 93% correct predictions, respectively).
- Combining these models into a consensus model enhances prediction performance to 94% and increases confidence in predicting chemical toxicity using these innovative approaches.
