Publications by authors named "Sam Lik-Fung Lau"
Article Synopsis
- The Mayo clinic imaging classification helps in better risk assessment for autosomal dominant polycystic kidney disease (ADPKD), but it struggles with diverse non-White populations and atypical imaging patterns.
- In a study of 98 Chinese ADPKD patients, 17% exhibited atypical imaging patterns, leading to later diagnosis and milder disease severity.
- Future genetic studies are needed to explore potential genotypic differences that might explain the varied phenotypic expressions seen in these patients.
Bioelectrical impedance analysis (BIA) has been extensively applied in nutritional assessments on the general population, and it is recommended in establishing the diagnosis of malnutrition and sarcopenia. The bioimpedance technique has become a promising modality through which to measure the whole-body composition in dialysis patients, where the presence of subclinical volume overload and sarcopenic obesity may be overlooked by assessing body weight alone. In the past two decades, bioimpedance devices have evolved from applying a single frequency to a range of frequencies (bioimpedance spectroscopy, BIS), in which the latter is incorporated with a three-compartment model that allows for the simultaneous measurement of the volume of overhydration, adipose tissue mass (ATM), and lean tissue mass (LTM).
View Article and Find Full Text PDFObjective: Patients with resolved hepatitis B virus (HBV) infection are at risk of HBV reactivation during treatment for hematological malignancies. We conducted a systematic review and meta-analysis of the data on the efficacy of antiviral prophylaxis for the prevention of HBV reactivation in this group of patients.
Methods: We conducted a systemic literature search of PubMed including MEDLINE and EMBASE databases to 31 January 2019 to identify studies published in English comparing antiviral prophylaxis with no prophylaxis for HBV reactivation in patients treated for hematological malignancies.