Publications by authors named "Sam Kharazi Neghad"
One of the most frequent environmental contaminants, benzene is still widely used as an industrial solvent around the world, especially in developing nations, posing a serious occupational risk. While the processes behind the toxicity of benzene grounds are not fully understood, it is generally accepted that its metabolism, which involves one or more reactive metabolites, is crucial to its toxicity. In order to evaluate the many ways that benzene could influence gene regulation and thus have an impact on human health, new methodologies have been created.
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- Exposure to air pollution leads to around seven million premature deaths and significantly contributes to disability, with particulate matter (PM) being a primary pollutant.
- PM2.5, due to its large surface area, can absorb harmful substances and cause cellular issues like oxidative stress, inflammation, and apoptosis.
- Non-coding RNAs (ncRNAs) are increasingly recognized for their role in responding to environmental changes, with exposure to PM2.5 linked to alterations in these ncRNAs, impacting health and disease processes.