Publications by authors named "Sam Heaton"
Article Synopsis
- The study focuses on periprosthetic fractures (PPFs) around the knee, examining patient demographics, fracture types, and treatment methods to assess their effect on in-hospital mortality.
- A total of 420 patients from a larger database were analyzed, revealing a 6.4% mortality rate; key risk factors included higher ASA grades, peripheral vascular disease, rheumatic disease, and fractures associated with loose implants.
- Management type did not significantly affect mortality, but surgical interventions led to longer hospital stays and increased likelihood of further surgeries compared to non-operative treatments.
Introduction: Periprosthetic fractures (PPFs) around the hip joint are increasing in prevalence. In this collaborative study, we aimed to investigate the impact of patient demographics, fracture characteristics, and modes of management on in-hospital mortality of PPFs involving the hip.
Methods: Using a multi-centre cohort study design, we retrospectively identified adults presenting with a PPF around the hip over a 10-year period.
Well-characterized antibody reagents play a key role in the reproducibility of research findings, and inconsistent antibody performance leads to variability in Western blotting and other immunoassays. The current lack of clear, accepted standards for antibody validation and reporting of experimental details contributes to this problem. Because the performance of primary antibodies is strongly influenced by assay context, recommendations for validation and usage are unique to each type of immunoassay.
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