Publications by authors named "Sam Fairclough"
Article Synopsis
- The study investigates the high prevalence of epilepsy in patients with WHO grade 2 glioma, finding that 86.4% had seizures either at diagnosis or later.
- It highlights that male patients are more likely to develop epilepsy and experience specific types of seizures, particularly those with left-sided tumors.
- The research suggests that patients who experience primarily motor seizures have a better overall survival rate, indicating that seizure activity could provide insight into prognosis regardless of other clinical factors.
Objective: The high seizure burden seen in World Health Association (WHO) grade 2 gliomas is well documented. This study aims to identify factors that influence the probability of seizure freedom (12 months of seizure remission) and treatment failure (antiseizure medication [ASM] cessation or introduction of an alternative) in patients with WHO grade 2 glioma.
Methods: This is a retrospective observational analysis of patients from a regional UK neurosurgical center with histologically proven (n = 146) WHO grade 2 glioma and brain tumor related epilepsy.
Auras and the risk of seizures with impaired consciousness following epilepsy surgery: implications for driving.
J Neurol Neurosurg Psychiatry
June 2018
Objective: To calculate the chance of a seizure in the next year (COSY) for seizures with impaired awareness in those experiencing auras only, those with no seizures and those with continuing seizures. Epilepsy surgery is an effective treatment for refractory focal epilepsy. Driving is an important factor affecting quality of life.
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