Epidemiology of infective endophthalmitis in France. The French Collaborative Study Group on Endophthalmitis.

Data from retrospective studies of endophthalmitis vary widely with respect to incidence and to the pathogens implicated. To see whether we could provide more accurate data, we have done a prospective multicentre national survey of endophthalmitis over one year in France. Records of 36,241 operations and 1148 cases of ocular trauma from 64 centres specialising in eye surgery were analysed.

[Diffusion of fluoroquinolones in the aqueous humor and crystalline lens].

In 53 patients undergoing cataract extraction, the authors measured pefloxacin and ofloxacin penetration in aqueous humour and lens. Cataract removal was performed at varying times after either the end of one-hour infusion of pefloxacin, ofloxacin per os in one time, or pefloxacin per os during 3 days. In the two first schemes, acme concentrations in aqueous humour are 1.

Pharmacokinetics of aztreonam in the aqueous humour.

Fifteen patients awaiting cataract extraction were given a 2 g intravenous bolus injection of aztreonam. The mean aztreonam concentrations in the aqueous humour. 1, 2 and 4 h after the injection were 1.

Pefloxacin concentrations in human aqueous humour and lens.

In 20 patients undergoing cataract extraction, we measured pefloxacin concentrations in the eye. After a 1 h infusion of pefloxacin 400 mg iv, the mean pefloxacin concentrations 2, 6, 12 and 24 h post-infusion were 0.75, 1.

[A case of cavernous hemangioma of the retina].

A case of hemangioma of the retina is reported. Its typical ophtalmoscopic and fluorescein angiographic aspects are studied. The benign evolution is stressed in spite of a possible macular risk checked by argon laser therapy.