Effect of oral administration of chlorine dioxide on hematological, physiological parameters and intestinal microbiota in a murine model.

Chlorine dioxide (CD) is a broad-spectrum disinfectant agent used to disinfect food products and, more recently, to treat diseases such as avian influenza and COVID-19 due to its potent antimicrobial properties. However, excessive use of chlorine dioxide can cause adverse health effects. While numerous in vivo studies have evaluated its toxicity CD's toxicity, few have investigated its impact on the intestinal microbiota.