Publications by authors named "Salvador Sanchez Majos"

A minimal setup for optoacoustic (OA) imaging requires an ultrasound probe and a pulsed laser. Such a system is capable of imaging small blood vessels and is sensitive to variations in their oxygen saturation. However, absolute oxygenation values cannot be obtained without a proper correction for the varying light fluence resulting from the optical attenuation in the surrounding tissue.

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Article Synopsis
  • Near-infrared optical tomography (NIROT) shows potential for studying brain function, but reconstructions can be affected by small surface features like birthmarks and hair.
  • Researchers tested whether artificial neural networks (ANN) could effectively address these surface perturbations in detecting brain activity.
  • The study found that ANNs can handle more significant skin variations than traditional Monte Carlo models, making them more effective for this purpose.
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In vivo imaging of tissue/vasculature oxygen saturation levels is of prime interest in many clinical applications. To this end, the feasibility of combining two distinct and complementary imaging modalities is investigated: optoacoustics (OA) and near-infrared optical tomography (NIROT), both operating noninvasively in reflection mode. Experiments were conducted on two optically heterogeneous phantoms mimicking tissue before and after the occurrence of a perturbation.

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The aim of this work was to measure optical properties of stool of mice to provide this relevant wavelength-dependent behavior for optical imaging modalities such as fluorescent molecular tomography and near-infrared optical tomography. BALB/c nude female mice were studied and optical properties of the stool were determined by employing the inverse adding-doubling approach. The animals were kept on chlorophyll-free diet.

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The accuracy of images obtained by Diffuse Optical Tomography (DOT) could be substantially increased by the newly developed time resolved (TR) cameras. These devices result in unprecedented data volumes, which present a challenge to conventional image reconstruction techniques. In addition, many clinical applications require taking photons in air regions like the trachea into account, where the diffusion model fails.

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