Moderately increased albuminuria unmasked hypertension.

The normal rate of albumin excretion is less than 30 mg/day (20 µg/min); persistent albumin excretion between 30 and 300 mg/day (20-200 µg/min) is called moderately increased albuminuria (formerly called microalbuminuria). In addition to being associated with diabetic nephropathy, moderately increased albuminuria has also been associated with cardiovascular disease in patients with as well as without diabetes. We present a case report of a man with moderately increased albuminuria who developed hypertension only detected by an ambulatory blood pressure monitoring procedure.

[In the identification of cardiovascular risk with the SCORE model, could we recommend its calculation interchangeably with total cholesterol or atherogenic index? Concordance between total cholesterol and atherogenic index in the SCORE table].

The SCORE table indiscriminately recommends the use of total cholesterol (SCORE-TC) or atherogenic index (SCORE-AI) for calculating cardiovascular (CV) risk. We evaluated reliability and agreement between both methods and the clinical implications for the identification of high CV risk. Observational study (n=8942) in a 40- to 65-year-old population.

Chronotherapy: a smart approach for refractory hypertension.

Patients with resistant hypertension are at greater risk for cardiovascular complications. Spreading out medication for the treatment of hypertension is a well known and widely used practice. Chronotherapy, the optimisation of schedules for administering drugs, constitutes a new option in optimising blood pressure control and reducing risk.

46 XX pure gonadal dysgenesis: an infrequent cause of primary amenorrhoea.

Amenorrhoea can be primary or secondary. Primary amenorrhoea is a relatively common problem among teenage girls. They usually consult their paediatrician or family doctor.