Publications by authors named "Salvador Eduardo Acevedo-Monroy"
UNAM-HIMFG Bacterial Lysate Activates the Immune Response and Inhibits Colonization of Bladder of Balb/c Mice Infected with the Uropathogenic CFT073 Strain.
Salvador Eduardo Acevedo-Monroy Ulises Hernández-Chiñas Luz María Rocha-Ramírez Oscar Medina-Contreras Osvaldo López-Díaz
Int J Mol Sci
September 2024
Urinary tract infections (UTIs) represent a clinical and epidemiological problem of worldwide impact that affects the economy and the emotional state of the patient. Control of the condition is complicated due to multidrug resistance of pathogens associated with the disease. Considering the difficulty in carrying out effective treatment with antimicrobials, it is necessary to propose alternatives that improve the clinical status of the patients.
View Article and Find Full Text PDFArticle Synopsis
- Overuse of antimicrobials has led to the rise of multidrug-resistant bacteria, complicating the treatment of infections like urinary tract infections (UTIs).
- Autologous bacterial lysates show promise as an alternative treatment for UTIs, but producing individual immunogens can be costly.
- A study on a polyvalent bacterial lysate containing 10 serotypes demonstrated safety in cell cultures and animals, while effectively stimulating the immune response, suggesting it could help manage chronic UTIs and reduce antimicrobial usage.