Direct statistical simulation of the Lorenz63 system.

We use direct statistical simulation to find the low-order statistics of the well-known dynamical system, the Lorenz63 model. Instead of accumulating statistics from numerical simulation of the dynamical system or solving the Fokker-Planck equation for the full probability distribution of the dynamical system, we directly solve the equations of motion for the low-order statistics after closing them by making several different choices for the truncation. Fixed points of the statistics are obtained either by time evolving or by iterative methods.

Drug Resistance in Nontuberculous Mycobacteria: Mechanisms and Models.

The genus comprises a multitude of species known to cause serious disease in humans, including and , the responsible agents for tuberculosis and leprosy, respectively. In addition, there is a worldwide spike in the number of infections caused by a mixed group of species such as the , and complexes, collectively called nontuberculous mycobacteria (NTMs). The situation is forecasted to worsen because, like tuberculosis, NTMs either naturally possess or are developing high resistance against conventional antibiotics.