Publications by authors named "Saloni Mehrotra"

Background: When viewed under near-infrared light, indocyanine green (ICG) signal for kidney perfusion can be utilized in partial nephrectomy. Laser speckle contrast imaging (LSCI) uses coherent light to detect perfusion during real-time laparoscopic surgery.

Materials And Methods: Laser speckle contrast imaging or ActivSight, an imaging sensor adapter, was used during laparoscopy of an anesthetized porcine kidney model.

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Article Synopsis
  • Real-time tissue perfusion measurement using Laser Speckle Contrast Imaging can enhance surgical decision-making by revealing ischemic changes in the intestines due to blood flow obstruction.
  • In a study with porcine models, the technique effectively distinguished between well-perfused and ischemic bowel segments under various occlusion scenarios.
  • Results showed a strong correlation between perfusion measurements and blood pressure changes, demonstrating that Laser Speckle could be used to assess and compare perfusion in different intestinal anastomosis techniques.
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Article Synopsis
  • Real-time intraoperative perfusion assessment using Laser Speckle Contrast Imaging (LSCI) could potentially minimize anastomotic leaks in surgeries by providing a dye-free visualization of blood flow in the intestines.
  • The ActivSight™ system, which can use both LSCI and indocyanine green imaging (ICG), was tested on porcine models to evaluate its effectiveness in quantifying intestinal perfusion under various experimental conditions.
  • Results showed that LSCI accurately differentiated between healthy and ischemic bowel regions, with quantification correlating well to blood pressure and the distance from ischemic areas, suggesting it offers a more objective assessment of bowel perfusion than traditional visual methods.
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Article Synopsis
  • Laser speckle contrast imaging (LSCI) is a technology used in robotic-assisted and laparoscopic surgeries to measure real-time tissue blood flow without the need for dye, offering advantages over traditional imaging methods like indocyanine green (ICG).
  • A study involving 67 patients assessed the effectiveness and usability of a new device that combines LSCI and ICG during various surgical procedures, revealing that both methods performed comparably in detecting perfusion.
  • Results showed no adverse effects and high usability ratings for surgeons, indicating that LSCI can be safely and effectively integrated into robot-assisted surgeries alongside laparoscopic techniques.
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