Publications by authors named "Saloa Saloa"
Genomics Inform
September 2022
Article Synopsis
- The Nervous necrosis virus (NNV) is a serious disease that impacts multiple fish species, employing a specific protein in grouper called GHSC70 to infiltrate host cells.
- The study aimed to assess 70 compounds derived from the Neem plant (Azadirachta indica) for their potential to block NNV by targeting GHSC70, as they have shown antiviral properties against other pathogens but not against NNV specifically.
- Using docking and molecular dynamics simulations, four compounds were identified as strong potential inhibitors, suggesting that Neem plant compounds could effectively prevent the viral entry; however, further lab testing is necessary to confirm their effectiveness.
