This study significantly concentrates on cryogenic InP HEMT high-frequency circuit analysis using quantum theory to find how the transistor nonlinearity can affect the quantum correlation of the modes generated. Firstly, the total Hamiltonian of the circuit is derived, and the dynamic equation of the motion contributed is examined using the Heisenberg-Langevin equation. Using the nonlinear Hamiltonian, some components are attached to the intrinsic internal circuit of InP HEMT to address the circuit characteristics fully.
View Article and Find Full Text PDFCirculating tumor cells are widely used as biomarkers of cancer. Although early detection of these cells is vital for diagnosis and prognosis of deadly cancer, it is still a challenging issue due to the complex matrix of blood and their low presence in the bloodstream. In the present study, we propose a micro-channeled lab-on-a-chip system using two distinct methods based upon dielectrophoretic force and electrical properties of cells to increase the cell detection capability and identification efficiency and accuracy.
View Article and Find Full Text PDFIn this article, a patch-clamp low noise current amplification based on nanoparticles plasmonic radiation is analyzed. It is well-known, a very small current is flowing from different membrane channels and so, for extra processing the current amplification is necessary. It is notable that there are some problems in traditional electronic amplifier due to its noise and bandwidth problem.
View Article and Find Full Text PDFIn this study, nanoparticles near-field plasmonic resonance is used to improve the traditional cell separation main outputs such as viability and efficiency. The live cells viability is severely depend on stresses, which are applied on cells in the microfluidics channel. Hence, for improving the cell viability, the enforced stresses inside of the structure should be declined.
View Article and Find Full Text PDFIEEE Trans Nanobioscience
September 2014
In this article, the nanoparticle-dye systems is designed and simulated to illustrate the possibility of enhancement in optical imaging contrast. For this, the firefly optimization technique is used as an optical signaling mechanism among agents (nanoparticle-dye) because fireflies attract together due to their flashing light and optical signaling that is produced by a process of bioluminescence (also it has been investigated that other parameters such as neural response and brain function have essential role in attracting fireflies to each other). The first parameter is coincided with our work, because the nanoparticle-dye systems have ability to augment of received light and its amplification cause that the designed complex system act as a brightness particle.
View Article and Find Full Text PDFIn this study, the authors investigate one of the biological sensory applications (fluorescence resonance energy transfer (FRET)) that has astonishing influence on implementation of the bio-medical assays. For the first time, in this study, the new inorganic modified nanoparticle structure (quantum-dot quantum-well (QDQW) heteronanocrystal) is used as donor particle. By considering the mentioned structure, the authors can easily manipulate the donor emission spectrum and all parameters of FRET, such as overlapping between the donor emission and acceptor absorption.
View Article and Find Full Text PDFIn this article, the targeting of dye molecules as an important goal is probed and simulated by quantum dots and through the particle swarm optimization algorithm and fluorescence resonance energy transfer mechanism. At first, we design a nano-bio sensor, based on the fluorescence resonance energy transfer mechanism, which operates in a wide range of wavelength and is very sensitive to fluorescence resonance energy transfer parameters such as overlapping between donor and acceptor, Föster radius, and energy transfer rate from donor to acceptor. In fact, the alteration of nano-bio sensor parameters acts as the heart of our sensor.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
May 2013
The main goal of this paper is to enhance the produced intensity radiation of nanoparticles that are functionalized to act as nano-biosensors in the biological applications, such as small tumor targeting and imaging. For example, in the optical imaging of the breast cancer, the numbers of photons that reach to the detector are very small because of the depth of the target and the loss of incident light due to absorption and scattering of the live cells and so on. Hence, the detection of small tumors is very difficult.
View Article and Find Full Text PDFCancer Nanotechnol
July 2011
In this article, the syntheses and optical properties of core/shell quantum dot (CdSe/ZnS) and their applications are reviewed. Nevertheless, the main focus is to provide an overview on biological applications of quantum dots that contain imaging, targeting, and sensing. We discuss the different synthetic methods, optical properties (photoluminescence intensity, absorption, and fluorescence spectra), and their dependence on shape, size, and inner structure of quantum dots.
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