Patterns of failure with F-DCFPyL PSMA-PET/CT in the post-prostatectomy setting: A regional cohort analysis.

Introduction: This study aimed to assess the detection rate of prostate cancer recurrence by prostate-specific member antigen positron emission tomography/computed tomography (PSMA PET/CT) with F-DCFPyL in patients with residual disease or biochemical recurrence (BCR), and its association with surgical pathology and prostate-specific antigen (PSA) kinetics.

Methods: Men from South Central Ontario enrolled in the PSMA Registry for Recurrent Prostate cancer (PREP) between April 2019 and December 2021 after radical prostatectomy (RP) and who had 1) pathologic stage N1 or persistent elevated PSA; or 2) BCR (PSA >0.10 ng/mL) where initial postoperative PSA was undetectable were included.

Towards sustainable development: Examining renewable energy consumption in E-7 countries.

In the contemporary landscape, sustainable development became major challenge for the economy which is tackled if environmental issues are resolved. In this regard, this study investigate renewable energy, institutional quality, foreign direct investment (FDI), economic growth on environmental pollution in E-7 countries (Brazil, Russia, China, Indonesia, India, Mexico, and Turkey). Utilizing annual data from 2002 to 2023, selected the panel Nonlinear Autoregressive Distributed Lag (NARDL) after applying stationary process.

A Review on Traditional and Artificial Intelligence-Based Preservation Techniques for Oil Painting Artworks.

Oil paintings represent significant cultural heritage, as they embody human creativity and historical narratives. The preservation of these invaluable artifacts requires effective maintenance practices to ensure their longevity and integrity. Despite their inherent durability, oil paintings are susceptible to mechanical damage and chemical deterioration, necessitating rigorous conservation efforts.

Efficacy and safety of peri-partum Esketamine for prevention of post-partum depression in women undergoing caesarian section: A meta-analysis and systematic review of randomized controlled trials.

Postpartum depression (PPD) is a psychiatric condition affecting women post-childbirth. Medication combined with psychotherapy, is the current protocol for its treatment. A meta-analysis was conducted using RevMan 5.

Work-related musculoskeletal disorders among information technology professionals in Riyadh, Saudi Arabia.

Background: This study was done to see the prevalence of work-related musculoskeletal disorders among information technology (IT) professionals in Saudi Arabia, the risk factors associated with them, their consequences, and to propose some preventive measures.

Material And Methods: A self-administered online questionnaire that included questions on the demographic data, job nature, medical history, work-related pain after joining information technology profession and distribution and severity of pain was sent to 250 information technology professionals working in Saudi Arabia.

Results: Out of 250, 202 (81%) IT professionals participated in the study.

Baseline Assessment of Health Research Systems in Saudi Arabia: Harnessing Efforts and Mobilizing Actions.

Major transformations are taking place in the Kingdom of Saudi Arabia (KSA) to achieve the 2030 vision for the health sector. A key component in strengthening the health system is a strong research governance strategy that can support the decision-making process by providing timely and accurate evidence that reflects local context and needs. This paper sought to better understand governance structures and policies for health research systems and support clusters so that they function effectively.

Outbreak investigation and identification of risk factors associated with the occurrence of foot and mouth disease in Punjab, Pakistan.

Foot-and-mouth disease (FMD) is a highly contagious viral disease of domesticated and wild ruminants and pigs that causes enormous economic losses through morbidity, mortality, and trade restrictions. Although the disease is endemic in Pakistan, seasonal outbreaks occur every year throughout the country. This study aimed to investigate FMD outbreaks and to identify the risk factors associated with FMD outbreaks between January and April 2019 in the Punjab province.

Overactive bladder: A multicenter study in Pakistan.

Objective: To determine the overall prevalence of overactive bladder in Pakistan, and to determine the difference in prevalence in relation to gender.

Methods: The multicenter study was conducted from February 2017 to October 2018 at 11 institutions across the country, and comprised randomly selected healthy subjects of either gender who were assessed on the basis of symptoms defined by the International Continence Society for overactive bladder. Data was collected using a questionnaire based on the symptoms which was filled for the respondent by designated health workers.

Doppler-Assessed Ureteric Jet Frequency: A Valuable Predictor of Ureteric Obstruction.

Objectives: To compare ureterovesical jet frequency in non-obstructed versus obstructed ureter secondary to ureteric stone using ultrasonography in patients presenting with ureteral stones.

Study Design:  Cross-sectional prospective study. Place of study and duration: Urology Department, The Kidney Centre Post Graduate Training Institute from May 16 to November 15, 2019.

Autonomous Assessment of Delamination Using Scarce Raw Structural Vibration and Transfer Learning.

Deep learning has helped achieve breakthroughs in a variety of applications; however, the lack of data from faulty states hinders the development of effective and robust diagnostic strategies using deep learning models. This work introduces a transfer learning framework for the autonomous detection, isolation, and quantification of delamination in laminated composites based on scarce low-frequency structural vibration data. Limited response data from an electromechanically coupled simulation model and from experimental testing of laminated composite coupons were encoded into high-resolution time-frequency images using SynchroExtracting Transforms (SETs).

Seroprevalence and Associated Risk Factors of Bovine Brucellosis in District Gujranwala, Punjab, Pakistan.

Bovine brucellosis is a contagious zoonotic disease that causes economic losses through abortion and infertility. A cross-sectional study was designed to determine the seroprevalence and associated risk factors of bovine brucellosis in district Gujranwala of Punjab, Pakistan. A total of 220 bovine sera (112 from buffaloes, 108 from cattle) from 46 unvaccinated herds were collected.

Comparative evaluation of upper versus lower calyceal approach in percutaneous nephrolithotomy (PCNL) for managing renal calculi.

Objective: To compare upper versus lower calyceal approaches in percutaneous nephrolithotomy for managing renal calculi.

Methods: The retrospective study was conducted in the Department of Urology, The Kidney Centre Post-Graduate Training Institute, Karachi, and comprised data of patients who underwent percutaneous nephrolithotomy from January 2014 to January 2015. Patients were divided into upper pole puncture group A and lower pole puncture group B.

Intelligent Steam Power Plant Boiler Waterwall Tube Leakage Detection via Machine Learning-Based Optimal Sensor Selection.

Boiler waterwall tube leakage is the most probable cause of failure in steam power plants (SPPs). The development of an intelligent tube leak detection system can increase the efficiency and reliability of modern power plants. The idea of e-maintenance based on multivariate algorithms was recently introduced for intelligent fault detection and diagnosis in SPPs.

Evolutionary Algorithm Based Capacity Maximization of 5G/B5G Hybrid Pre-Coding Systems.

Hybrid pre-coding strategies are considered as a potential solution for combating path loss experienced by Massive MIMO systems operating at millimeter wave frequencies. The partially connected structure is preferred over the fully connected structure due to smaller computational complexity. In order to improve the spectral efficiency of a partially connected hybrid pre-coding architecture, which is one of the requirements of future 5G/B5G systems, this work proposes the application of evolutionary algorithms for joint computation of RF and the digital pre-coder.

A review on numerical modeling for magnetic nanoparticle hyperthermia: Progress and challenges.

Recent progress in nanotechnology has advanced the development of magnetic nanoparticle (MNP) hyperthermia as a potential therapeutic platform for treating diseases. Due to the challenges in reliably predicting the spatiotemporal distribution of temperature in the living tissue during the therapy of MNP hyperthermia, critical for ensuring the safety as well as efficacy of the therapy, the development of effective and reliable numerical models is warranted. This article provides a comprehensive review on the various mathematical methods for determining specific loss power (SLP), a parameter used to quantify the heat generation capability of MNPs, as well as bio-heat models for predicting heat transfer phenomena and temperature distribution in living tissue upon the application of MNP hyperthermia.

Outcome of 980 nm diode laser vaporization for benign prostatic hyperplasia: A prospective study.

Purpose: To evaluate the initial experience and outcome of photo-selective vaporization of the prostate (PVP) for benign prostatic hyperplasia (BPH) in Pakistan with the use of a 980 nm diode laser.

Materials And Methods: A prospective study was performed from November 2016 to December 2017. A total of 100 patients diagnosed with bladder outlet obstruction secondary to BPH who planned for PVP were enrolled in the study.

Postoperative Pain Score of Bupivacaine versus Placebo in Patients Undergoing Percutaneous Nephrolithotomy.

Objective: To compare postoperative mean pain score of bupivacaine versus placebo in patients undergoing percutaneous nephrolithotomy.

Study Design: An experimental study.

Place And Duration Of Study: Department of Urology, The Kidney Centre, Postgraduate Training Institute (PGTI), Karachi, from November 2014 to December 2015.

Novel approach to coronary artery perforation repair.

Coronary artery perforation (CAP) during percutaneous coronary intervention is a rare but serious complication. Treatment options of CAP include prolonged balloon inflation, covered stent, and coil embolization. Although most cases of CAP can be treated with prolonged balloon inflation, some cases, especially Ellis grade III CAP require covered stents or coiling.

Stenosis Caused by Suture-Mediated Vascular Closure Device in an Angiographic Normal Common Femoral Artery: Its Mechanism and Management.

Vascular closing devices (VCDs) are widely used to replace manual compression at the femoral puncture site and to reduce the discomfort of patients undergoing percutaneous coronary procedure by shortening bed rest. Among the vascular complications related to these devices, the femoral artery stenosis or occlusion is rarely reported, and its standard management is not well established. We report a case of symptomatic femoral artery stenosis caused by suture-mediated VCD and managed using rotational atherectomy device and balloon angioplasty.

Late-Onset Nonthrombotic Left Common Iliac Vein Compression Secondary to Degenerative Lumbar Disc: A Case Report of May-Thurner Variant.

May-Thurner syndrome (MTS) refers to venous outflow obstruction caused by extrinsic compression of the left common iliac vein (LCIV) by the overlying pulsatile right common iliac artery against lumbar vertebrae. The classic clinical presentation is acute unilateral left leg painful swelling due to deep venous thrombosis in a young woman in the second or third decade of life. We present a case of a 66-year-old woman who presented with late-onset left leg swelling caused by nonthrombotic venous hypertension due to degenerative lumbar disc bulge leading to LCIV compression against the left common iliac artery which was confirmed by computed tomography and intravascular ultrasound.

Predictive Factors for Intraoperative Blood Loss during Percutaneous Nephrolithotomy.

Objective: To evaluate the factors that may increase bleeding during Percutaneous nephrolithotomy (PCNL) and correlate them with outcome.

Study Design: Analytical study.

Place And Duration Of Study: The Kidney Centre postgraduate Training Institute, Karachi, Pakistan, from July to December 2016.

Awareness of risk factors and fallacies associated with urinary bladder cancer in our population: A prospective survey.

Objective: To determine the awareness of risk factors for bladder cancer and false beliefs associated with this disease.

Methods: This cross-sectional study was conducted at the Kidney Centre, Karachi, from January to February 2015, and comprised subjects who presented to the various in-house clinics. The subjects were interviewed using a questionnaire comprising demographic parameters, level of education and awareness of smoking hazards, knowledge and false beliefs associated with bladder cancer.