Publications by authors named "Salma Y Abu El-Nazar"

Introduction: Lupus nephritis (LN) is a common complication of systemic lupus erythematosus. Vitamin D and cycline-dependent kinase-1 (CDK1) have been implicated in its pathogenesis. The aim of this study was to determine the relation between vitamin D level and CDK-1 in lupus nephritis patients and their impact on disease activity.

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Breast cancer is the most common gynecological malignancy in the world. In Egypt, it ranks the first among female malignancies with incidence of 37.7%.

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Gamma radiation radiotherapy is one of the widely used treatments for cancer. There is an accumulating evidence that adaptive immunity is significantly contributes to the efficacy of radiotherapy. This study is carried out to investigate the effect of gamma rays on the interplay between Th1/Th2 response, splenocyte lymphoproliferative response to polyclonal mitogenic activators and lymphocytic capacity to produce IL-12 and IL-10 in mice.

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Synopsis of recent research by authors named "Salma Y Abu El-Nazar"

  • - Salma Y Abu El-Nazar's research primarily focuses on the implications of various biological factors, such as vitamin D levels and gene expression, in disease conditions like lupus nephritis and breast cancer, as evidenced in her studies highlighting the correlation between vitamin D and cyclin-dependent kinase-1 in patients with lupus nephritis.
  • - One significant finding from her work indicates the role of NY-BR-1 antigen expression in Egyptian breast cancer patients, suggesting its relevance in both clinicopathological assessment and the prognosis of the disease, underscoring the need for further exploration of biomarkers in cancer.
  • - Additionally, her investigation into the effects of gamma radiation on immune responses demonstrates how murine models can provide insights into the mechanisms of radiotherapy, enhancing understanding of the adaptive immune system's role in cancer treatment outcomes.