Specialty follow -up care after hospital discharge of patients with multisystem inflammatory syndrome in children associated with COVID-19 from a rural tertiary-care hospital.

Background: The clinical features of Multisystem Inflammatory Syndrome in Children (MIS-C) have been well documented, but there is limited data regarding the short term and longitudinal outcomes of children living in rural areas. We report the demographic and clinical features, as well as the multi-specialty follow-up of patients with MIS-C served by a large tertiary care rural health system.

Methods: Patients that met the Centers for Disease Control (CDC) case definition of MIS-C admitted between March 1, 2020, and March 31, 2021, were included in this case series.

Gender Differences in Research Productivity of Academic Physicians Before and During the COVID-19 Pandemic.

The gendered impact of the COVID-19 on scientific productivity has been primarily studied in nonclinical academic fields. We investigated the gendered effect of the pandemic on diverse measures of research participation among physician faculty, who experienced an increase in clinical duties concomitant with pandemic-era challenges to research. Physician faculty employed in both 2019 (prepandemic) and 2021 (pandemic era) were identified at one U.

Rapid biosynthesis and characterization of metallic gold nanoparticles by olea europea and their potential application in photoelectrocatalytic reduction of 4-nitrophenol.

In recent years, photoelectrocatalysis of gold nanoparticles (Au NPs) has received considerable attention due to their potential to improve catalytic efficiency. Herein, ultra-small Au NPs were successfully synthesized in a single pot using olea europea leaf extract as a green reducing agent for the degradation of 4-nitrophenol. The TEM images showed uniform distribution and spherical shape of Au NPs with an average diameter of 5 nm.

Solithromycin in Children and Adolescents With Community-acquired Bacterial Pneumonia.

Background: Solithromycin is a new macrolide-ketolide antibiotic with potential effectiveness in pediatric community-acquired bacterial pneumonia (CABP). Our objective was to evaluate its safety and effectiveness in children with CABP.

Methods: This phase 2/3, randomized, open-label, active-control, multicenter study randomly assigned solithromycin (capsules, suspension or intravenous) or an appropriate comparator antibiotic in a 3:1 ratio (planned n = 400) to children 2 months to 17 years of age with CABP.

Influence of measles-mumps-rubella vaccine series initiation and completion on influenza vaccination among adolescents.

Background: Influenza vaccine participation in adolescents is low. Barriers to the influenza vaccine may be shared with the measles-mumps-rubella (MMR) vaccine.

Methods: We studied adolescents aged 13-17 years who participated in the National Immunization Survey-Teen between 2011 and 2017 (N = 129,200).

Association between asthma and influenza vaccine uptake among US adolescents: a retrospective survey study.

Objective: Despite longstanding recommendations for children with asthma to receive the influenza vaccine, vaccine uptake in this population remains low. We used the nationally representative National Immunization Survey-Teen to analyze the impact of asthma on adolescent influenza vaccination rates.

Methods: Adolescents ages 13-17 years with provider-reported data on vaccine coverage were included in the analysis.

The influence of local political trends on childhood vaccine completion in North Carolina.

Background: In North Carolina (NC), a political swing state that permits both medical and religious exemptions to school vaccination, rapid changes in the electorate have coincided with a vigorous political debate over vaccine laws and an increase in the number of exemptions claimed from vaccine requirements.

Objective: We aimed to determine whether county-level changes in political affiliation, determined from publicly available voting records, were associated with changes in the rate of vaccine exemptions reported at kindergarten entry in NC.

Methods: We analyzed data from the 2009-2010 to the 2016-2017 school years for each of 100 NC counties.

Assessment of biomarkers of cardiovascular risk among HIV type 1-infected adolescents: role of soluble vascular cell adhesion molecule as an early indicator of endothelial inflammation.

Cardiovascular disease (CVD) biomarkers were examined in a cohort of HIV-infected and HIV-uninfected adolescents who participated in Adolescent Trials Network study 083 utilizing samples from the Reaching for Excellence in Adolescent Care cohort, a longitudinal study of youth infected through adult risk behavior. Nonfasting blood samples from 97 HIV-infected and 81 HIV-uninfected adolescents infected by adult risk behaviors were analyzed for total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), triglycerides, apolipoprotein A-I, high-sensitivity C-reactive protein (hsCRP), soluble vascular adhesion molecule-1 (sVCAM-1), myeloperoxidase, and neopterin at baseline and 18 months later. Results were analyzed using ANOVA, Wilcoxon signed-rank, and paired t tests.

Prevalence of hicAB, lav, traA, and hifBC among Haemophilus influenzae middle ear and throat strains.

Nontypeable Haemophilus influenzae (NTHi) is an important cause of illness among children. To further understand the role of laterally transferred genes in NTHi colonization and otitis media, the prevalence of hicAB, lav, tnaA, and hifBC was determined among 44 middle ear and 35 throat NTHi isolates by dot-blot hybridization.