Publications by authors named "Salma Elhag"

Article Synopsis
  • The study investigated the expression of relaxin-2 (RLN2) and its potential role in differentiated thyroid cancer (DTC) using tissue samples from 181 DTC patients and 185 individuals with benign thyroid conditions.
  • Results showed that RLN2 was significantly higher in DTC tissue compared to adjacent non-tumor tissue, alongside elevated levels of total macrophages (CD68) and immunosuppressive M2 macrophages (CD163).
  • The findings suggest that RLN2 could serve as a valuable biomarker for thyroid cancer, indicating possible therapeutic targets and the influence of immune cells in thyroid carcinogenesis.
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Article Synopsis
  • The study investigates the prevalence and causes of sleep disturbances in individuals with type 2 diabetes (T2DM) during the COVID-19 pandemic, finding that about 35.8% reported poor sleep quality.
  • Researchers analyzed data from 288 T2DM patients in Qatar, using various statistical methods to explore relationships between sleep quality and factors like age, depression, and stress.
  • The results indicate that high depression scores and a history of sleep disorders are significant predictors of poor sleep quality, emphasizing the need for healthcare providers to address these issues in T2DM patients.
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Chest X-ray (CXR) imaging is a standard and crucial examination method used for suspected cases of coronavirus disease (COVID-19). In profoundly affected or limited resource areas, CXR imaging is preferable owing to its availability, low cost, and rapid results. However, given the rapidly spreading nature of COVID-19, such tests could limit the efficiency of pandemic control and prevention.

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Medulloblastoma (MB) is a malignant pediatric brain tumor with a poor prognosis. Post-surgical radiation and cisplatin-based chemotherapy have been a mainstay of treatment, which often leads to substantial neurocognitive impairments and morbidity, highlighting the need for a novel therapeutic target to enhance the sensitivity of MB tumors to cytotoxic therapies. We performed a comprehensive study using a cohort of 71 MB patients' samples and pediatric MB cell lines and found that MB tumors have elevated levels of nucleosome remodeling FACT (FAcilitates Chromatin Transcription) complex and DNA repair enzyme AP-endonuclease1 (APE1).

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This case report demonstrates the benefit of using the shortened dental arch (SDA) design for a comprehensive implant-supported restoration and the avoidance of the complexities of implant placement near the maxillary sinus. The SDA concept as a treatment option is encouraging in terms of function, patient satisfaction, and cost-effectiveness.

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Eruption disorders are numerous varying from delayed to complete failure of eruption. Primary failure of eruption (PFE) is a rare condition that involves arrested eruption of teeth with the absence of local or general contributory factors. Another rare and clinically challenging phenomenon is canine transmigration which is the intra-osseous movement of impacted canines across the midline.

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Pentalogy of Cantrell is a syndrome that consists of five anomalies: a midline, upper abdominal wall abnormality; lower sternal defect; anterior diaphragmatic defect; diaphragmatic pericardial defect, and congenital abnormalities of the heart. The pathogenesis of this condition is not fully known yet, associations are common with this condition and treatment is extremely challenging. Prognosis and outcome depends on the type of the pentalogy of Cantrell and associated cardiac anomalies.

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Objective: To determine secreted antischistosoma antibodies in urine and to discern the epidemiological situation of schistosomiasis in the agricultural field labourers'camps city in the Gezira State-central Sudan.

Methods: Total of 66 urine and 66 serum paired samples were collected from those who confirmed parasitologically positive and negative with schistosomiasis from the two camps. Samples were tested using ELISA technique to measure and compare the immunoglobulin G (IgG) levels in serum and urine samples of schistosomiasis patients.

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