Release of vasopressin during suppression of oestrous cycle in rat by zoladex and hypovolemic challenge.

Background: The vasopressin (AVP) response to hypovolemia has been compared in intact and chemically castrated rats. This functional ovariectomy was done to confirm the findings in surgical ovariectomy of how gonadal steroids modulate the release of AVP under hypo-volemic challenge.

Methods: Twenty female Sprague Dawley rats were checked for oestrous over two consecutive cycles.

Effect of tamoxifen on pituitary vasopressin level.

Background: Estrogens modulate the release of Arginine Vasopressin (AVP). There is an increased level of AVP in plasma and pituitary under osterogen hormones.

Methods: Ten rats were experimental and ten were controls.