Publications by authors named "Sally Pilling"
Clostridium difficile infection (CDI) has been primarily treated with metronidazole or vancomycin. High recurrence rates, the emergence of epidemic PCR ribotypes (RTs) and the introduction of fidaxomicin in Europe in 2011 necessitate surveillance of antimicrobial resistance and CDI epidemiology. The ClosER study monitored antimicrobial susceptibility and geographical distribution of C.
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- * The study tested MCB3681 against 199 strains of infection using PCR ribotyping, comparing its effectiveness to 8 other antibiotics, including metronidazole and vancomycin.
- * Results indicated that MCB3681 was effective, with no signs of resistance found in bacterial isolates already resistant to other antibiotics like moxifloxacin and linezolid.