Mayo Clin Proc Innov Qual Outcomes
March 2018
Objective: To compare perinatal outcomes, blood pressures throughout pregnancy, rates of hypertensive disorders of pregnancy, preeclampsia, gestational diabetes mellitus, and immediate obstetric outcomes in adolescents younger than 20 years at delivery and those in the 20- to 34-year age group.
Patients And Methods: Questionnaires were administered to pregnant women at Campbelltown and Liverpool hospitals within South West Sydney, Australia, as part of a broader study of sleep-disordered breathing in pregnancy between February 1, 2009, and February 28, 2013. Data collected included demographic data, blood pressure readings, pregnancy complications, delivery type, and neonatal outcomes.
Background: There is recent interest exploring the possible impact of sleep disordered breathing on the mechanisms of preeclampsia. A biomarker of preeclampsia, soluble fms-like tyrosine kinase-1, has come to prominence in recent years. The aim of this study was to investigate the relationship between continuous positive airway pressure treatment, sleep disordered breathing and soluble fms-like tyrosine kinase-1 concentrations during pregnancy.
View Article and Find Full Text PDFStudy Objectives: To evaluate the ability of the Sonomat to diagnose obstructive sleep apnea (OSA).
Design: Prospective and randomized.
Setting: Sleep laboratory and home.
Objective: The objective of this study was to determine what impact the omission of respiratory events scored during wake epochs has on the generation of the apnea/hypopnea index (AHI) using computerised polysomnography (PSG).
Materials And Methods: Sixty diagnostic PSG recordings were scored using the recommended method of sleep staging with epochs. In addition, absolute sleep scoring criteria was used to calculate the total sleep time (TST).
Background And Objective: While recent meta-analyses suggest that OSA elevates daytime blood pressure (BP), most studies have included patients with mild hypertension, so CPAP treatment has only reduced BP by 2-3 mm Hg. To determine the strength of the OSA-BP relationship, this study examined the effect of CPAP in a cohort where severe OSA and under-treated hypertension coexist.
Methods: Baseline demographic and sleep study data were recorded in 221 consecutive patients referred for sleep studies in Samoa.
Obstructive sleep apnea can be diagnosed in approximately 60% of stroke survivors in the postacute period and has been found to be associated with increased mortality and a worse functional outcome at 3 and 12 mo after discharge. In this study, 38 patients undergoing rehabilitation after stroke underwent sleep studies by using the AutoSet Portable II Plus device; obstructive sleep apnea was found in 18 of the patients, and five consecutively diagnosed patients were treated on the ward with nasal continuous positive airway pressure. The research has shown that it is feasible to routinely implement a diagnostic and therapeutic approach to sleep apnea on the rehabilitation ward, which is hoped to have a positive influence on mortality, functional outcome, and secondary prevention.
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