Publications by Sally B Morton

Publications by authors named "Sally B Morton"

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Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links.

Sally B Morton L David Finger Roxanne van der Sluijs William D Mulcrone Michael Hodskinson

J Am Chem Soc

January 2023

DNA interstrand cross-links (ICLs) prevent DNA replication and transcription and can lead to potentially lethal events, such as cancer or bone marrow failure. ICLs are typically repaired by proteins within the Fanconi Anemia (FA) pathway, although the details of the pathway are not fully established. Methods to generate DNA containing ICLs are key to furthering the understanding of DNA cross-link repair.

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