Publications by authors named "Salim Kemal Tuncer"
Objectives: Paraquat (PQ) is a widely used herbicide. Exposure to PQ at toxic doses can result in fatal acute lung injury. Inhibition of the poly-(ADP-ribose) polymerase (PARP) enzyme alleviates inflammation and necrosis in various pathologies.
View Article and Find Full Text PDFBackground/aim: Urticaria is a vascular skin reaction characterized with papules and plaques. Neopterin is accepted as an immunologic marker and an indicator of activation of the immune system. Homocysteine and asymmetric dimethylarginine (ADMA) are the markers of increased vascular resistance.
View Article and Find Full Text PDFSerum neuron-specific enolase (NSE) and S-100β levels are considered novel biochemical markers of neuronal cell injury. In this study, the initial and post-treatment levels of NSE and S-100β were compared in carbon monoxide (CO) poisoning patients, who received normorbaric oxygen (NBO) or hyperbaric oxygen (HBO) therapy. Forty consecutive patients with acute CO poisoning were enrolled in this prospective, observational study.
View Article and Find Full Text PDFEvaluation of autopsy reports in terms of preventability of traumatic deaths.
Ulus Travma Acil Cerrahi Derg
March 2015
Background: The analysis of autopsy reports plays an important role in the evaluation of trauma care quality. The objective of this study was to determine the rate of preventable deaths and medical errors in regard to the autopsy reports as an indicator of trauma care quality in traumatic deaths.
Methods: A retrospective review of traumatic autopsy reports kept between 2011 and 2012 in Eskişehir, Turkey was conducted.
Background: Soft tissue trauma is a type of acute traumatic ischemia. We investigated in this study whether the edema, inflammation and ischemia caused by the trauma could be affected positively by hyperbaric oxygen (HBO) and ozone therapy.
Methods: Soft tissue trauma was generated in a total of 63 adult male Sprague-Dawley rats.
Article Synopsis
- Landmine injuries often result in significant damage to the heel, making reconstruction difficult, but long-term outcomes have not been well-researched.
- A case-control study involving nine male patients who underwent heel reconstruction and ten healthy volunteers revealed no major differences in functional ambulation and basic walking tests, although reconstruction patients scored lower in general health and vitality.
- Overall, combat-injured veterans with heel reconstructions had satisfactory long-term mobility, indicating the importance of early rehabilitation and collaboration between medical professionals for better patient outcomes.
Various therapeutic protocols were used for the management of sepsis including hyperbaric oxygen (HBO) therapy. It has been shown that ozone therapy (OT) reduced inflammation in several entities and exhibits some similarity with HBO in regard to mechanisms of action. We designed a study to evaluate the efficacy of OT in an experimental rat model of sepsis to compare with HBO.
View Article and Find Full Text PDFObjectives: Ischemia-modified albumin (IMA) is an emerging diagnostic biomarker for many ischemic conditions. This study was conducted to investigate whether there is a change in IMA levels in carbon monoxide (CO) poisoning and, if so, the clinical relevance of IMA levels.
Methods: This cohort study, performed between November 2008 and April 2009, compared the serum IMA levels of 33 CO-poisoned patients taken at the time of presentation at the emergency department and after 3 hours of treatment and 49 healthy controls.