Publications by authors named "Salihah Lau"
Our previous study demonstrated that the acute high-dose-rate (3.3 Gy/min) γ-ray irradiation (γ-irradiation) of postnatal day-3 (P3) mice with 5 Gy induced depression and drastic neuropathological changes in the dentate gyrus of the hippocampus of adult mice. The present study investigated the effects of chronic low-dose-rate (1.
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- The study investigates the effects of chronic low dose radiation exposure during prenatal and postnatal stages on neurological health, specifically focusing on potential links to neuropsychiatric disorders and changes in the hippocampus in mice.
- Findings show no significant cellular or cognitive impairments in the irradiated mice, but there were noticeable reductions in body weight and exploratory behavior, alongside changes in organ weights without abnormal pathology.
- Molecular analysis revealed specific genes and microRNAs were altered in the hippocampus and blood of irradiated mice, indicating a biological response to radiation exposure despite the absence of major neurological symptoms.