Publications by authors named "Salgunan Nair"
Article Synopsis
- The PROSE trial aimed to compare the On-X mechanical prosthesis with the St Jude Medical mechanical prosthesis for thromboembolic complications.
- The study involved 855 subjects across 28 centers from 2003 to 2016 and found no significant differences in thromboembolism or mortality rates between the two prostheses at the 5-year mark.
- Notable differences were observed in valve thrombosis occurrences based on valve position and between Western and Developing populations, with Developing populations experiencing more complications, particularly in the mitral valve position.
Objectives: The PROSE trial purpose is to investigate whether the incidence of thromboembolic-related complications is reduced with a current generation mechanical prosthesis (On-X Life Technologies/CryoLife Inc.-On-X) compared with a previous generation mechanical prosthesis (St Jude Medical-SJM). The primary purpose of the initial report is to document the preoperative demographics, and the preoperative and operative risk factors by individual prosthesis and by Western and Developing populations.
View Article and Find Full Text PDF