Extreme droughts in the Amazon Basin during cyclic ENSO events coupled with Indian Ocean Dipole modes and Tropical North Atlantic warming.

The teleconnections between El Niño-Southern Oscillation (ENSO), the Indian Ocean Dipole (IOD), and Tropical North Atlantic warming (+TNA) play a critical role in characterizing extreme drought events in the Amazon Basin (AB). This study examines the seven most recent drought extreme events up to 2023, using seasonal composites of the sea surface temperature and atmospheric variables over a five-quarter period starting at the austral spring(-1) of the year preceding that when the lowest water level at Manaus port was recorded. Two distinct patterns emerge, driven by consecutive ENSO events with opposite phases, referred to as cyclic La Niña-El Niño and cyclic El Niño-La Niña drought events.

Isotemporal substitution of physical activity patterns and sitting time with obesity indicators among workers in São Paulo.

This study aimed to evaluate the association between substituting 10, 30, and 60 min/day of physical activity and sitting time with obesity indicators among workers. It is a cross-sectional study involving 394 adults (76.6% women) from São Paulo, Brazil.

Exploring the biosorption of nickel and lead by Fusarium sp. biomass: kinetic, isotherm, and thermodynamic assessment.

Fungal biomass is as a cost-effective and sustainable biosorbent utilized in both active and inactive forms. This study investigated the efficacy of inactivated and dried biomass of Fusarium sp. in adsorbing Ni and Pb from aqueous solutions.

Efficient photocatalytic degradation of diclofenac drug using the ZnPrAlO photocatalyst under UV light irradiation.

Herein, we report the efficient photocatalytic degradation of the diclofenac drug using the ZnPrAlO photocatalyst [x, y] = (0.00, 0.00), (0.

Assessment of health-related quality of life after mild COVID-19 infection.

Introduction: Coronavirus disease 19 (COVID-19) affected the health-related quality of life (HRQoL), and its impact on well-being is not sufficiently understood yet. The worsening of HRQoL and symptoms such as fatigue, anxiety, depression, chronic Headache, Myalgia, ageusia, olfactory disorders, and cognitive impairment can be seen in people of different ages and genders after COVID-19 infection, even mild infections without hospitalization. These issues generate a disease burden that can reduce work skills and cause social, psychological, and neuropsychiatric challenges.

Wind power density in areas of Northeastern Brazil from Regional Climate Models for a recent past.

Investments in renewable energy sources are increasing in several countries, especially in wind energy, as a response to global climate change caused by the burning of fossil fuels for electricity generation. Thus, it is important to evaluate the Regional Climate Models that simulate wind speed and wind power density in promising areas for this type of energy generation with the least uncertainty in recent past, which is essential for the implementation of wind farms. Therefore, this research aims to calculate the wind power density from Regional Climate Models in areas at Northeast of Brazil from 1986 to 2005.

Comparative assessment of growth curves in Brazilian white Morada Nova hair sheep breed.

The Morada Nova sheep breed is essential for the economy of the semi-arid region of Northeast Brazil, standing out for its adaptability, resistance to parasites and reproductive ability. However, the white variant is endangered, highlighting the importance of studies on its productivity to support conservation efforts. This study focuses on the growth curve of the Morada Nova sheep breed, using nonlinear models and analyzing flock profiles.

Effect of ripening time on the content of bioactive peptides and fatty acids profile of Artisanal Coalho cheese.

The present study aimed to investigate the influence of ripening on the physicochemical, microbiological aspects, and fatty acid profile of Artisanal Coalho Cheeses and to detect if there are peptides with bioactive potential in their composition. Artisanal Coalho Cheese samples were kindly provided by a dairy farm located in Brazil in the Rio Grande do Norte state. A completely randomized design was adopted, with four maturation periods (0, 30, 45, and 60 days).

Biology of the non-parasitic phase of the cattle tick Rhipicephalus (Boophilus) microplus in an area of Amazon influence.

Background: Rhipicephalus (Boophilus) microplus is the most important tick species affecting cattle in the world. Under field conditions, the non-parasitic phase of R. (B.

A far-ultraviolet-driven photoevaporation flow observed in a protoplanetary disk.

Most low-mass stars form in stellar clusters that also contain massive stars, which are sources of far-ultraviolet (FUV) radiation. Theoretical models predict that this FUV radiation produces photodissociation regions (PDRs) on the surfaces of protoplanetary disks around low-mass stars, which affects planet formation within the disks. We report James Webb Space Telescope and Atacama Large Millimeter Array observations of a FUV-irradiated protoplanetary disk in the Orion Nebula.

Effect of milk exposure on the redox profile of Caenorhabditis elegans.

The consumption of bovine milk and its derivatives is associated with inflammation, gastrointestinal disorders and the development of diseases in humans. Most studies related to milk effects are based on either clinal trials or experimental models such as mice and cell cultures. In this study we present the nematode Caenorhabditis elegans as an alternative model to evaluate the effects of milk on oxidative stress in other animal models.

Effective adsorption of cadmium and nickel ions in mono and bicomponent systems using eco-friendly adsorbents prepared from peanut shells.

The work investigates the potential of peanut shells, an abundant agro-industrial waste, to serve as an adsorbent precursor for the effective and simple treatment of effluents loaded with cadmium and nickel ions. Among the adsorbents prepared, carbonized peanut shell (C), due to its higher adsorption capacity, proved to be the most effective compared to carbonized and activated peanut shell (C). The carbonization process led to structural changes, which resulted in an increase in surface area (around 6 times more in C) and pore volume (around 3 times more in C).

An Overview of the Occurrence of Bioactive Peptides in Different Types of Cheeses.

The search for improvements in quality of life has increasingly involved changes in the diet, especially the consumption of foods which, in addition to having good nutritional value, are characterized by offering health benefits. Among the molecules that trigger several beneficial responses are peptides, which are specific fragments of proteins known to produce positive effects on the human body. This review aimed to discuss the bioactive potential of peptides from cheeses.

Characterization of Physicochemical and Sensory Properties of Cheeses Added with Bovine Colostrum.

The objective of this study was to develop fresh and matured cheeses with different bovine colostrum levels, aiming to promote the consumption of dairy products with the addition of colostrum. Four different cheese formulations were produced with a mixture of 0:100, 15:85, 20:80, and 25:75, bovine colostrum:milk (:), and aged for 0, 10, 20, and 40 days. Milk, colostrum, and fresh and matured cheeses were submitted to physicochemical characterization.

A longitudinal analysis of the fluctuation of food stores in Belo Horizonte, Minas Gerais, Brazil.

Background: Changes in food environments have the potential to affect consumption, nutritional status, and health, and understanding these changes is of utmost importance. This study, therefore, aimed to examine the fluctuation of food stores that sell fruits and vegetables over five years in the health promotion service area of Primary Health Care (PHC) in Belo Horizonte, Minas Gerais, Brazil.

Methods: This was an ecological study that used data from a food environment audit conducted in the realm of Brazilian PHC.

Dual nanocarrier of chlorhexidine and fluconazole: Physicochemical characterization and effects on microcosm biofilms and oral keratinocytes.

Objectives: This study assembled and characterized a dual nanocarrier of chlorhexidine (CHX) and fluconazole (FLZ), and evaluated its antibiofilm and cytotoxic effects.

Methods: CHX and FLZ were added to iron oxide nanoparticles (IONPs) previously coated by chitosan (CS) and characterized by physical-chemical analyses. Biofilms from human saliva supplemented with Candida species were grown (72 h) on glass discs and treated (24 h) with IONPs-CS carrying CHX (at 39, 78, or 156 µg/mL) and FLZ (at 156, 312, or 624 µg/mL) in three growing associations.

Thermal and Mechanical Properties of Reprocessed Polylactide/Titanium Dioxide Nanocomposites for Material Extrusion Additive Manufacturing.

Polylactic acid (PLA) is a biodegradable polymer that can replace petroleum-based polymers and is widely used in material extrusion additive manufacturing (AM). The reprocessing of PLA leads to a downcycling of its properties, so strategies are being sought to counteract this effect, such as blending with virgin material or creating nanocomposites. Thus, two sets of nanocomposites based respectively on virgin PLA and a blend of PLA and reprocessed PLA (rPLA) with the addition of 0, 3, and 7 wt% of titanium dioxide nanoparticles (TiO) were created via a double screw extruder system.

Manufacture and Characterization of Polylactic Acid Filaments Recycled from Real Waste for 3D Printing.

This paper studies the thermal, morphological, and mechanical properties of 3D-printed polylactic acid (PLA) blends of virgin and recycled material in the following proportions: 100/0, 25/75, 50/50, and 75/25, respectively. Real waste, used as recycled content, was shredded and sorted by size without a washing step. Regular dog-bone specimens were 3D printed from filaments, manufactured in a single screw extruder.

Synthesis of chalcones and their antimicrobial and drug potentiating activities.

The increased resistance of microorganisms to antimicrobial drugs makes it necessary to search for new active compounds, such as chalcones. Their simple chemical structure makes them molecules easy to synthesize. Therefore, the aim of this study was to evaluate the antimicrobial and potentiating activity of antibiotics and antifungals by synthetic chalcones against strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and Candida tropicalis.

Association between school environment with sedentary behavior and physical activity intensity in children.

We examined the association between indicators of the school environment with sedentary behavior and different intensities of physical activity in children. The study that included 515 children (265 boys) aged 9-11 years old from public and private schools in the city of São Caetano do Sul. Sedentary behavior and different intensities of physical activity were evaluated with an accelerometer.

Apigenin improves cytotoxicity of antiretroviral drugs against HTLV-1 infected cells through the modulation of AhR signaling.

Objectives: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory autoimmune disease characterized by high levels of infected immortalized T cells in circulation, which makes it difficult for antiretroviral (ART) drugs to work effectively. In previous studies, we established that Apigenin, a flavonoid, can exert immunomodulatory effects to reduce neuroinflammation. Flavonoids are natural ligands for the aryl hydrocarbon receptor (AhR), which is a ligand activated endogenous receptor involved in the xenobiotic response.

Antifungal effect of the liposome encapsulation of the Trans- Caryophylene and its association with fluconazole.

Trans-Caryophyllene (TC), a sesquiterpene, with proven biological activities, which in this work was tested alone, encapsulated in liposomes and associated with Fluconazole in vitro in an attempt to enhance the effect of the drug. Liposomes were characterized from vesicle size, polydispersity index, and Zeta potential, and imaging by scanning electron microscopy. Antifungal assays were performed against Candida albicans, Candida tropicalis and Candida krusei by microdilution to determine the IC values and the viability curve.

UPLC-MS-ESI-QTOF Analysis and Antifungal Activity of Aqueous Extracts of .

This study aimed to identify the chemical composition of the aqueous leaf and root extracts (EALST and EARST) and to evaluate their effect, comparatively, against opportunistic pathogenic fungi. Ultra-Performance Liquid Chromatography Coupled to a Quadrupole/Time of Flight System (UPLC-MS-ESI-QTOF) was employed for chemical analysis. and standard strains and clinical isolates were used (CA INCQS 40006, CT INCQS 40042, CA URM 5974, and CT URM 4262).