Publications by authors named "Salekh Aliev"
Gut Microbiota and Cytokine Profile in Cirrhosis.
J Clin Transl Hepatol
August 2024
Article Synopsis
- * Specific cytokines such as IL-1b, IL-6, and TNF-a were associated with both higher levels of harmful gut bacteria and the severity of cirrhosis symptoms like ascites, suggesting a connection between gut health and liver disease progression.
- * The results indicate that certain gut bacteria populations correlate directly with inflammatory cytokine levels, pointing to a potential link between gut dysbiosis and systemic inflammation in cirrhosis patients.
Our aim was to study the association of endothelial dysfunction biomarkers with cirrhosis manifestations, bacterial translocation, and gut microbiota taxa. The fecal microbiome was assessed using 16S rRNA gene sequencing. Plasma levels of nitrite, big endothelin-1, asymmetric dimethylarginine (ADMA), presepsin, and claudin were measured as biomarkers of endothelial dysfunction, bacterial translocation, and intestinal barrier dysfunction.
View Article and Find Full Text PDFObjectives: The aim is to study impact of vaccination against the novel coronavirus disease (COVID-19) with Sputnik V on mortality during the period of predominance of the delta variant of SARS-CoV-2.
Methods: This was a retrospective cohort study of individuals with state health insurance at the Moscow Ambulatory Center. The cohorts included 41,444 persons vaccinated with Sputnik V, 15,566 survivors of COVID-19, and 71,377 non-immune persons.
Background: The clinical efficacy and safety of vaccination against novel coronavirus disease 2019 (COVID-19) in patients with cirrhosis have not been evaluated yet.
Aim: To evaluate the clinical efficacy and safety of vaccination against COVID-19 in patients with cirrhosis.
Methods: This was a retrospective cohort study of patients with cirrhosis.
Application of Polymer Drugs with Cerium Dioxide Nanomolecules and Mesenchymal Stem Cells for the Treatment of Skin Wounds in Aged Rats.
Polymers (Basel)
May 2021
Unlabelled: The urgency of the problem of wound healing is not in doubt, given the global trend of an increase in the number of operations and injuries with skin damage, as well as the lack of universal means of treating wounds.
Study Objective: To compare the effectiveness of the developed drugs, smart polymeric nano-drug with cerium oxide nanoparticles (SPN), and smart polymeric nano-drug in combination with mesenchymal stem cells (SPN + SC) on the healing process of skin wounds.
Material And Methods: An experimental study was carried out using Wistar rats of post-reproductive age, which had dermis and epidermis removed on their backs.
Purpose: To study the effects of inflammation on the healing process of rats' acute skin wounds during treatment with different injections.
Methods: The study was carried out on Wistar rats, on which square wounds were simulated in the back region. Four groups of wounds were studied.