Tris(4-chlorophenyl)methane and tris(4-chlorophenyl)methanol disrupt pancreatic organogenesis and gene expression in zebrafish embryos.

Objectives: Tris(4-chlorophenyl) methane (TCPM) and tris(4-chlorophenyl)methanol (TCPMOH) are anthropogenic environmental contaminants believed to be manufacturing byproducts of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) due to environmental co-occurrence. TCPM and TCPMOH are persistent, bioaccumulate in the environment, and are detected in human breast milk and adipose tissues. DDT exposures have been previously shown to disrupt insulin signaling and glucoregulation, increasing risk for diabetes.

Association between particulate matter air pollution and heart attacks in San Diego County.

Air pollution is one of the major risk factors contributing to adverse public health outcomes worldwide. Fine particulate matter (PM) has been repeatedly associated with increased risk of cardiovascular events, including heart attacks. Because PM is unequally distributed with elevated concentrations near high-traffic and industrial zones, PM is an environmental justice issue of major public health concern.