Diet Supplementation with Pomegranate Fruit Alters Distal Gut Microbiota of Healthy Female College Students.

Pomegranate is a fruit that grows abundantly in the Middle East and Africa. It is rich in polyphenols, sugars, fiber, and vitamins, and has long been associated in traditional and alternative medicine with numerous health benefits, including the treatment of diarrhea and gut inflammation. We assessed how regular daily intake of fresh pomegranate can affect the distal gut microbiota of young healthy female students in Egypt, a region with abundant pomegranate production and frequent occurrence of gut dysbiosis.

The relationship between blood pressure and mortality after subarachnoid haemorrhage.

Background: Blood pressure monitoring and management are critical nursing tasks in patients with aneurysmal subarachnoid haemorrhage (SAH). Yet, it remains unclear to several bedside nurses whether high or low blood pressure is associated with better outcomes.

Aim: The aim of this study was to investigate whether blood pressure predicts mortality and hospital length of stay in patients with aneurysmal SAH.

Anti-MRSA effects of synergism of recombinant lysostaphin with biosynthesized silver nanoparticles.

Background: Methicillin-resistant (MRSA) strains become a major challenge to public health and health provider due to their wide spread and resistance to wide spectrum of antibacterial agents.

Aim: This study aimed to characterize recombinant lysostaphin produced by BL21(DE3) and to investigate the biosynthesis of silver nanoparticles (SNPs) by against MRSA.

Methods: Samples were collected from vaginal samples.

Reduced autoimmunity associated with deletion of host CD73.

CD73 is ubiquitously expressed and regulates critical functions across multiple organ systems. The sequential actions of CD39 and CD73 accomplish the conversion of adenosine triphosphate to adenosine and shift the adenosine triphosphate-driven proinflammatory immune cell milieu toward an anti-inflammatory state. This immunological switch is a major mechanism by which regulatory T (Treg) cells control inflammation.

Comprehensive In Vitro Evaluation of Antibacterial, Antioxidant, and Computational Insights into (L.) B. L. Burtt from Hail Mountains, Saudi Arabia.

The arid mountainous region of Hail in Saudi Arabia has a variety of desert vegetation, some of which are conventionally used in Bedouin traditional medicine. These plants need scientific examination. This research seeks to examine using a thorough multi-analytical methodology that includes antibacterial and antioxidant assessments as well as computational modeling.

Metabolites in the Dance: Deciphering Gut-Microbiota-Mediated Metabolic Reprogramming of the Breast Tumor Microenvironment.

Breast cancer (BC), a major cause of death among women worldwide, has traditionally been linked to genetic and environmental factors. However, emerging research highlights the gut microbiome's significant role in shaping BC development, progression, and treatment outcomes. This review explores the intricate relationship between the gut microbiota and the breast tumor microenvironment, emphasizing how these microbes influence immune responses, inflammation, and metabolic pathways.

Perception, knowledge, and factors influencing Saudi nursing students toward practicing testicular self-examination: A cross-sectional study.

Background: Testicular cancer poses a substantial health burden globally, and early detection through testicular self-examination (TSE) is vital for improving prognosis. The study aims to assess the perception, awareness, knowledge, and factors associated with TSE among Saudi nursing students.

Materials And Methods: A structured questionnaire was distributed to 418 participants.

The psychological impact of COVID-19 on front-line healthcare providers in the United Arab Emirates: A cross-sectional study.

Background: The COVID-19 pandemic has significantly impacted the psychological well-being of healthcare providers (HCPs) worldwide. Understanding the prevalence and associated factors of depression, generalized anxiety disorder (GAD), and posttraumatic stress disorder (PTSD) among these providers is crucial. Assess the prevalence of major depression, GAD, and PTSD symptoms among HCPs in the United Arab Emirates (UAE) during the COVID-19 pandemic.

Reducing sedentary behavior improves depressive symptoms among patients with heart failure enrolled in a home-based mobile health app cardiac rehabilitation.

Background: Depressive symptoms are common, worsening heart failure (HF) progression and reducing quality of life. While supervised structured exercise training is effective for managing depressive symptoms, it often demands a substantial time commitment or intensive activity that may discourage participation.

Objective: Evaluate the impacts of reducing sedentary time with short bouts of light physical activities or greater intensity levels on depressive symptoms after HF patients' enrollment in a home-based intervention.

Limosilactobacillus reuteri ameliorates maternal separation stress in newborn mice and alters subsequent adult behaviour.

Maternal separation (MS) in mice results in behavioral deficits and gut microbiota dysbiosis that all persist into adulthood. Limosilactobacillus reuteri DSM 17938 modulates gut microbiota, alters systemic metabolites, and facilitates immune regulation. To assess the effect of DSM 17938 on biochemical and behavioural stress-associated changes, newborn mice were exposed to unpredictable MS (MSU) daily from day 7 to day 20 of life, with intragastric administration of DSM 17938 or PBS as control.

Multidrug resistance and phylogenetic analyses of based on the gene of isolates recovered from clinical samples and their susceptibility to silver-nanoparticle.

Background: is a highly antimicrobial-resistant pathogen with a very narrow range of effective antibacterial agents. Therefore, finding alternative compounds is highly required, such as silver nanoparticles (AgNPs).

Aim: The current study was conducted to identify the multidrug resistance (MDR) profile and perform a phylogenetic analysis on isolates recovered from clinical samples (human, cows, cats, and fish) and to study their susceptibility to AgNPs.

Assessing the impact of a respiratory care bundle on health status and quality of life of chronic obstructive pulmonary disease patients in Jordan: A quasi-experimental study.

Background: This study aimed to evaluate the effectiveness of a respiratory care bundle, including deep breathing exercises, incentive spirometry, and airway clearance techniques, on the quality of life (QoL) of chronic obstructive pulmonary disease (COPD) patients in Jordan.

Materials And Methods: A quasi-experimental study design and convenience sampling method was used to recruit 120 COPD patients, with 54 in the intervention group and 66 in the control group. The intervention group received additional respiratory care bundle training, while the control group received only discharge instructions and an education program.

Digesting Digital Health: A Study of Appropriateness and Readability of ChatGPT-Generated Gastroenterological Information.

Introduction: The advent of artificial intelligence-powered large language models capable of generating interactive responses to intricate queries marks a groundbreaking development in how patients access medical information. Our aim was to evaluate the appropriateness and readability of gastroenterological information generated by Chat Generative Pretrained Transformer (ChatGPT).

Methods: We analyzed responses generated by ChatGPT to 16 dialog-based queries assessing symptoms and treatments for gastrointestinal conditions and 13 definition-based queries on prevalent topics in gastroenterology.

Optimizing outcomes in paraesophageal hernia repair: a novel critical view.

Background: The recurrence rate of paraesophageal hernia repair (PEHR) is high with reported rates of recurrence varying between 25 and 42%. We present a novel approach to PEHR that involves the visualization of a critical view to decrease recurrence rate. Our study aims to investigate the outcomes of PEHR following the implementation of a critical view.

Exploring the Impact of Cardiac Rehabilitation Programs on Health-Related Quality of Life and Physiological Outcomes in Patients Post Coronary Artery Bypass Grafts: A Systematic Review.

Background: This systematic review explores the impact of cardiac rehabilitation programs (CRPs) on health-related quality of life (HRQoL) and physiological outcomes post-coronary artery bypass graft (CABG) surgery. Acknowledging the increasing importance of CRPs in post-CABG care, the study emphasizes the need for a comprehensive evaluation of their effectiveness. The primary objective is to investigate how CRPs influence HRQoL and physiological outcomes in post-CABG patients, offering insights into the multifaceted impact of these rehabilitation programs.

The contribution of household income to rectal cancer patient characteristics, treatment, and outcomes from 2010 to 2020.

Background: There is a paucity of recent literature investigating the sole effect of income level on the treatment and survival of patients with rectal cancer.

Methods: We analyzed all cases of rectal cancer in the Rectal Cancer PUF of the NCDB from 2010 to 2020. We utilized the Median Income Quartiles 2016-2020 to define our income levels.

"We do others' Jobs": a qualitative study of non-nursing task challenges and proposed solutions.

Introduction: Non-nursing tasks (NNTs) have become a prevalent issue among healthcare professionals, affecting nurses globally. This study delves into the experiences of Jordanian nurses regarding NNTs, aiming to uncover challenges and propose solutions within the Jordanian healthcare context.

Objective: Explore the impact of NNTs on Jordanian nurses' roles, workload, and satisfaction.

Pancreatitis as a Pulmonary Pathology: A Rare Case of a Pancreaticopleural Fistula Presenting as Recurrent Pleural Effusions Causing Mediastinal Shift.

Pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis and pancreatic pseudocyst. It can present as recurrent pleural effusions and can be difficult to diagnose and treat. We present the case of a 37-year-old male with a history of chronic idiopathic pancreatitis complicated by a pseudocyst who came in with progressive dyspnea, cough, and pleuritic chest pain.