Publications by authors named "Saleh Khudirat"
Article Synopsis
- Multiparametric flow cytometry (MFC) is used for diagnosing and managing B-cell acute lymphoblastic leukemia (B-ALL) by monitoring leukemic cell characteristics and minimal residual disease (MRD) during treatment.
- This study investigated the role of the myeloid marker CD371 in MRD detection for patients diagnosed with CD371-positive B-ALL, analyzing data from 238 patients over critical treatment periods.
- Findings showed that 8.4% of B-ALL patients were CD371-positive, with specific associations to age and other leukemic markers, suggesting that CD371 status in patients may provide critical insights for future research and treatment approaches.
Background: The introduction of checkpoint inhibitors in solid cancer therapy showed successful results. The role of Programmed Death-1/Programmed Death-Ligand 1 (PD1/PD-L1) in hematologic malignancies is currently being investigated and clinical trials are ongoing. Preliminary findings showed conflicting results.
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