Protective effects of pyridoxine, amlodipine, and their combination in a vasopressin-induced angina model in rats.

Vitamin B6 (pyridoxine) vitamins are of interest in preventative and protective strategies in cardiovascular disease. However, the safety and efficacy of vitamin B6 has been questioned. The aim of this study was to study the protective effect of pyridoxine, amlodipine, and their combination against vasopressin-induced angina model in rats.

Acute and sub-chronic toxicological evaluation of Averrhoa carambola leaves in Sprague Dawley rats.

Averrhoa carambola is a species of tree native to tropical Southeast Asia. It possesses antioxidant and anti-hyperlipidemia effects and has traditionally been used to treat a variety of ailments. However, the presence of oxalic acid in its fruits might restrict its consumption by individuals suffering from kidney disease, and caramboxin can cause neurotoxicity.