Publications by authors named "Salari M"

In this study, minced turkey meat samples were subjected to electron-beam irradiation with dosages of 0, 1.5, 3, and 5 kGy, and then microbial (mesophilic and psychrotrophic bacteria), physiochemical (pH, water activity [a], thiobarbituric acid reactive substances [TBARS], and peroxide value [PV]), and sensory (color, odor, texture, and overall acceptability) analyses were performed at 0 and 6 months of freezing storage (-18°C). Results showed that by 5 kGy irradiation and freezing treatments, the counts of psychrotrophic and mesophilic bacteria reduced remarkably ( < 0.

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Background: Each of the Coronavirus disease 2019 (COVID-19) vaccines has its characteristics that can affect their effectiveness in preventing hospitalization and patient mortality. The present study aimed to determine the effectiveness of COVID-19 vaccines, including whole-virus, protein-based, and vector-based on COVID-19 infection, hospitalization, and mortality.

Methods: The current cohort study was conducted using the data of all people who received at least two doses of each type of COVID-19 vaccine from March 2020 to August 2022 in Khorasan Rzavi province.

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MXene has garnered growing interest in the field of electrochemistry, thanks to its unique electrical and surface characteristics. Nonetheless, significant challenges persist in realizing its full potential in chemoresistive sensing applications. In this study, a novel unidirectional freeze-casting approach for fabricating a Poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS)-facilitated vertically aligned MXene-based aerogel with enhanced chemoresistive sensing properties was introduced.

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Background: Oxidative stress damages biological molecules and plays a role in aging-related cardiovascular diseases. is a major source of antioxidants that may work against age-related cardiovascular changes.

Aims: This study aimed to assess the changes in electrocardiography and lipid profile as well as indicators of the oxidant-antioxidant system with advanced age in rats.

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Background: Trials demonstrated an increased risk of distal median nerve dysfunction (DMND) and carpal tunnel syndrome (CTS) associated with teriflunomide in people with multiple (pwMS).

Objective: To estimate the real-world prevalence of clinical CTS and electrodiagnostic DMND in teriflunomide-treated pwMS.

Methods: Cross-sectional study on selected teriflunomide (WHOATC code: L04AK02)-treated, risk factor-free pwMS at the Isfahan MS clinic in 2022.

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Brain stimulation has been recognized as a clinically effective strategy for treating neurological disorders. Endogenous brain neural precursor cells (NPCs) have been shown to be electrosensitive cells that respond to electrical stimulation by expanding in number, undergoing directed cathodal migration, and differentiating into neural phenotypes in vivo, supporting the application of electrical stimulation to promote neural repair. In this study, we present the design of a flexible and biodegradable brain stimulation electrode for temporally regulated neuromodulation of NPCs.

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The objective was to develop an active chitosan-based coating and to evaluate its effect on the shelf life and microbial safety of bread. Bacterial cellulose nanofibers (BCNF) and various levels (0.5%, 1%, and 2%) of silver nanoparticles (AgNPs) were in the chitosan (CS) film.

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Article Synopsis
  • * The study analyzed 85 urine samples from welders, revealing both metals were present in all samples, with average concentrations of 1.09 µg/g for Ni and 11.45 µg/g for Cr.
  • * Significant correlations were found between the concentrations of these metals and factors like education, income, lifestyle choices, and workplace conditions, suggesting lifestyle determinants and lack of protective measures are key predictors of heavy metal levels.
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  • Primary Hemifacial Spasm (pHFS) is linked to facial nerve compression from blood vessels, with studies showing women are affected about twice as often as men, though there's conflicting evidence regarding which side of the face is more commonly impacted.* -
  • The review examined existing literature to identify anatomical factors that could influence the development of HFS and its gender/side preference, finding that both sides are generally affected equally, but specific vascular anatomical variations may lead to side preferences.* -
  • Key anatomical variations, particularly in posterior circulation, may heighten the risk for HFS, with some indications of a tendency toward the left side, yet there's limited research on the differences between men and women, indicating a need for more
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  • A recent study examined a condition called "pure spinal" MS, which features demyelination mainly in the spinal cord, potentially responding well to disease-modifying treatments (DMT).
  • Researchers analyzed data from around 8000 patients and identified 7 women with this condition, averaging 40 years old and having positive markers in their cerebrospinal fluid indicative of demyelination.
  • Treatment with DMT resulted in reduced relapse rates and stabilization of symptoms in these patients, suggesting that pure spinal MS may merit further study and could lead to updates in diagnostic criteria for MS.
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Despite the availability of statins and lifestyle modifications, many patients with Dyslipidemia struggle to achieve optimal low-density lipoprotein cholesterol (LDL-C) control. PCSK9 inhibitors offer a promising new therapeutic option with superior LDL-C lowering efficacy compared to statins. However, data on their real-world use, particularly in Iran, is limited.

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Background: Pediatric-onset multiple sclerosis (POMS) cases, defined as multiple sclerosis (MS) with onset before the age of 18, represent between 3 and 5 % of all MS patients. Anti-CD20 drugs mainly rituximab, ocrelizumab, and ofatumumab are being widely used in adult-onset MS. Their use in POMS is also being increasingly considered by experts.

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Introduction: Neuromyelitis Optica Spectrum Disorders (NMOSD) is a neuroinflammatory condition characterized by optic neuritis and transverse myelitis. While the current approach to NMOSD focuses on relapse-associated worsening (RAW), recent evidence indicates Relapse-Independent Disease Activity (RIDA) in patients.

Method: Databases including Embase, PubMed, Scopus, and Web of Sciences were systematically searched up to December 2023.

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Introduction And Importance: Stiff person syndrome (SPS) is a rare autoimmune disorder that affects the central nervous system. Patients with this condition may experience sudden muscle spasms, leading to falls and subsequent fractures. Diagnosis is based on clinical presentation, the presence of anti-GAD antibodies, and electromyography (EMG) findings that show continuous motor unit activity.

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Objective: To review cases of optic neuritis after COVID-19 vaccination and add similar cases to the literature.

Methods: Thorough PubMed and Scopus searches were conducted, and data from studies describing optic neuritis after COVID-19 vaccination were extracted, tabulated, pooled, and reviewed.

Results: We present 6 cases of optic neuritis following COVID-19 vaccination.

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Electromagnetic pollution presents growing challenges due to the rapid expansion of portable electronic and communication systems, necessitating lightweight materials with superior shielding capabilities. While prior studies focused on enhancing electromagnetic interference (EMI) shielding effectiveness (SE), less attention is given to absorption-dominant shielding mechanisms, which mitigate secondary pollution. By leveraging material science and engineering design, a layered structure is developed comprising rGOnR/MXene-PDMS nanocomposite and a MXene film, demonstrating exceptional EMI shielding and ultra-high electromagnetic wave absorption.

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Objective: We aim to evaluate the prevalence of depression in disorders including multiple sclerosis (MS), Parkinson's disease (PD), migraine, and stroke. Also, we detect risk factors for depression occurrence within each disorder. Moreover, we compare the risk factors in these four common neurologic disorders.

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: Postoperative agitation is a common complication of sevoflurane anesthesia in children and might lead to self-harm and recovery disruption. This study aimed to compare the prophylactic effect of dexmedetomidine and remifentanil on postoperative agitation after anesthesia with sevoflurane. : In this clinical trial, 60 children aged 2 to 7 years with ASA class І, II, candidates for elective strabismus surgery, were randomly assigned to three groups using block randomization.

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Characteristics of livers and spleens of people with multiple sclerosis (pwMS) could constitute good biomarkers of MS-related characteristics such as the disability status. To test the hypothesis "the gross anatomical features of livers and spleens, are not similar between pwMS with different disease characteristics" a cross-sectional study was conducted on pwMS seen at the Isfahan MS clinic, Iran, from February until December 2023. Definitive, otherwise-healthy, pwMS were enrolled after an initial laboratory evaluation.

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Introduction: Freezing of gait can be seen in a significant number of people with Parkinson's disease. Disappointingly, the classic standard treatment of Parkinson's disease with dopamine replacement has not shown promising results in improving the freezing of gait. Hence the approach have shifted towards using non-invasive methods to address this problem.

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Article Synopsis
  • Measles remains a significant public health issue in Hormozgan province, Iran, where a study analyzed outbreaks from 2014 to 2019, revealing that 151 out of 1291 suspected cases were confirmed through RT-PCR testing.
  • The demographic data showed an average age of confirmed cases was 16.77 years, with most cases occurring in 2015, while vaccination status revealed 68.2% were unvaccinated.
  • The findings indicate critical gaps in vaccination coverage and effectiveness, highlighting the need for better immunization strategies and public health measures to manage measles in the region.
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Background: Exposure to physical contamination during chemotherapy, including non-ionizing electromagnetic fields, raises concerns about the widespread sources of exposure to this type of radiation. Glioblastoma multiforme (GBM) is an aggressive central nervous system tumor that is hard to treat due to resistance to drugs such as temozolomide (TMZ).

Objective: Electromagnetic fields (EMF) and haloperidol (HLP) may have anticancer effects.

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Rationale: Probiotics have beneficial effects on the nervous system by modulating the gut-brain axis. Additionally, vitamin D supplementation presents a potential way for ameliorating neuropsychological disorders, particularly in regions with a high prevalence of vitamin D deficiency.

Objectives: The current clinical trial aimed to investigate the role of co-administered supplementation of probiotics and Vitamin D on the different inflammatory aspects of patients with Parkinson's disease.

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Current therapeutic approaches for Huntington's disease (HD) focus on symptomatic treatment. Therefore, the unavailability of efficient disease-modifying medicines is a significant challenge. Regarding the molecular etiology, targeting the mutant gene or advanced translational steps could be considered promising strategies.

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Background: Magnetic resonance imaging [MRI] findings in Neuromyelitis optica spectrum disorder [NMOSD] and Multiple Sclerosis [MS] patients could lead us to discriminate toward them. For instance, U-fiber and Dawson's finger-type lesions are suggestive of MS, however linear ependymal lesions raise the possibility of NMOSD. Recently, artificial intelligence [AI] models have been used to discriminate between NMOSD and MS based on MRI features.

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